Visceral fat impairs memory via proinflammatory interleukin-1 beta mediated microglia activation in the hippocampus.
By inhibiting a particular receptor microglia use to survive, researchers reduced neuroinflammation and prompted recovery following traumatic brain injury in mouse models.
The NLPR3 inflammasome and the inflammatory response it triggers play a critical role in the emergence of tau pathology.
SARM, an ancient immune protein previously implicated in apoptosis, is a key immune regulator in peripheral immune cells. The finding could help in the development of treatments for a range of diseases, including Alzheimer's, cancer and diabetes.
Researchers report an inflammatory mechanism within the brain's immune system may drive the progression of Alzheimer's disease.
Researchers reveal how the macrophages become inflamed as we age and prevent neurotransmitters from functioning correctly.
Findings could help guide researchers to develop new drugs to treat Multiple Sclerosis and other neurological diseases.
Sleep may be regulated by inflammasome NLRP3, researchers report.
A new study may pinpoint an alternative treatment for people with drug resistant multiple sclerosis.
A new study reports a commonly used NSAID anti-inflammatory drug was able to reverse memory loss in mouse models of Alzheimer's disease.
