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neuropharmacology

Featured Genetics Neurology Neuroscience Pain

·April 23, 2025·4 min read

Clearing Zombie Cells Eases Back Pain

A new preclinical study has found that two drugs—o-Vanillin and RG-7112—can clear “zombie cells” from spinal discs, potentially treating the root cause of chronic low back pain. These senescent cells accumulate with age or injury and cause inflammation, pain, and tissue damage.

Featured Neuroscience

·April 22, 2025·7 min read

Reading Brainwaves to Fine-Tune Consciousness in Surgeries

A new clinical trial shows that using EEG to guide anesthesia in children significantly reduces the amount of anesthetic needed while improving post-surgery recovery. By monitoring brain wave patterns, anesthesiologists maintained safe unconsciousness with lower doses of sevoflurane, leading to faster awakening and fewer cases of post-anesthesia delirium.

Featured Neuroscience Psychology

·April 18, 2025·5 min read

Potential Depression Risk Linked to Ozempic-Like Drugs

A new international study reveals a possible connection between GLP1 receptor agonists—used in drugs like Ozempic—and increased risk of depression and suicidal ideation, especially in people with low dopamine function. Researchers used advanced pharmacogenomic tools to identify genetic pathways that may be vulnerable to dopamine dysregulation when exposed to these medications.

Featured Neurology Neuroscience

·April 16, 2025·5 min read

Ozempic Linked to Lower Alzheimer’s Risk

A new study suggests that two widely used Type 2 diabetes medications—GLP-1 receptor agonists and SGLT2 inhibitors—may help reduce the risk of Alzheimer’s disease and related dementias. Researchers analyzed Medicare data and found that patients taking these drugs had significantly lower rates of cognitive decline compared to those using other glucose-lowering medications.

Brain Cancer Featured Neurology Neuroscience

·April 9, 2025·3 min read

Chemotherapy Disrupts Brain Connectivity

New research reveals that chemotherapy can lead to rapid and widespread changes in brain connectivity in breast cancer patients. Using functional MRI scans, scientists observed disruptions in the frontal-limbic system and cerebellar cortex, regions involved in executive function and memory.

Featured Neurology Neuroscience Pain

·March 14, 2025·6 min read

Cannabis Terpenes Offer New Hope for Chronic Pain, Fibromyalgia

New research has identified cannabis-derived terpenes—compounds that give plants their distinctive aroma—as effective treatments for fibromyalgia and post-surgical pain. In preclinical mouse models, terpenes such as geraniol and linalool significantly reduced chronic pain, providing promising alternatives to opioid medications and avoiding THC's psychoactive side effects.

Featured Neurology Neuroscience

·March 6, 2025·2 min read

Long-Term NSAID Use Linked to Lower Dementia Risk

A new study finds that long-term use of non-steroidal anti-inflammatory drugs (NSAIDs) is associated with a lower risk of developing dementia. Researchers followed 11,745 adults over 14.5 years and found that those who used NSAIDs long-term had a 12% reduced dementia risk.

Featured Neuroscience Psychology

·February 14, 2025·6 min read

Prozac Shows Promise in Fighting Infections & Sepsis

New research suggests that fluoxetine, commonly used as an antidepressant, may also help protect against infections and sepsis. Scientists found that the drug has antimicrobial properties and helps regulate the immune response, reducing the risk of tissue and organ damage.

Featured Neuroscience

·February 12, 2025·7 min read

Semaglutide Shows Promise in Reducing Alcohol Cravings and Consumption

A new study suggests that semaglutide, a drug commonly used for diabetes and obesity, may also help reduce alcohol consumption. Researchers found that weekly injections of semaglutide decreased alcohol cravings, drinking quantity, and heavy drinking days in adults with alcohol use disorder. Participants receiving semaglutide consumed less alcohol in a controlled lab setting and reported reduced cravings compared to those receiving a placebo.

Featured Neuroscience Pain

·February 6, 2025·6 min read

How CBD Modulates THC’s Impact on the Brain

Researchers have identified how CBD interacts with cannabinoid receptors to mitigate the negative effects of THC, the psychoactive component of cannabis. Unlike THC, which fully activates the receptor and causes side effects like memory loss and addiction, CBD acts as a modulator, fine-tuning receptor activity.

Featured Neurology Neuroscience

·January 21, 2025·6 min read

Antibiotics and Other Drugs May Reduce Dementia Risk

A study analyzing data from over 130 million individuals found that antibiotics, antivirals, vaccines, and anti-inflammatory medications are associated with a reduced risk of dementia. This supports the idea that infections and inflammation contribute to dementia and highlights the potential of repurposing existing drugs for prevention or treatment.

This shows the outline of a person and a brain.

Featured Neuroscience

·January 20, 2025·6 min read

GLP-1 Drugs Offer Brain Benefits but May Pose Other Health Risks

A study analyzing data from over 2 million veterans found that GLP-1 receptor agonists, popular weight-loss drugs like Ozempic and Wegovy, provide significant neurological and behavioral health benefits, including reduced risks of addiction, Alzheimer’s, and dementia. However, they also pose risks for pancreatitis and kidney conditions, emphasizing the need for careful monitoring.

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neuropharmacology

Clearing Zombie Cells Eases Back Pain

Reading Brainwaves to Fine-Tune Consciousness in Surgeries

Potential Depression Risk Linked to Ozempic-Like Drugs

Ozempic Linked to Lower Alzheimer’s Risk

Chemotherapy Disrupts Brain Connectivity

Cannabis Terpenes Offer New Hope for Chronic Pain, Fibromyalgia

Long-Term NSAID Use Linked to Lower Dementia Risk

Prozac Shows Promise in Fighting Infections & Sepsis

Semaglutide Shows Promise in Reducing Alcohol Cravings and Consumption

How CBD Modulates THC’s Impact on the Brain

Antibiotics and Other Drugs May Reduce Dementia Risk

GLP-1 Drugs Offer Brain Benefits but May Pose Other Health Risks

Prenatal Lead Exposure Affects the Aging Brain

Uncanny Average: Most People Can No Longer Spot an AI Face

Predicting Autism Traits Through Infant Sleep

New Bio-Implant for Spinal Cord Repair

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