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neuropharmacology

This shows a man holding a wine glass against a psychedelic backdrop.

·November 10, 2025·4 min read

Psychedelics Calm Stress Circuits to Reduce Alcohol Drinking

New research shows that psilocin, the active metabolite of the psychedelic psilocybin, may reduce alcohol consumption by calming stress-sensitive neurons in the central amygdala. In female mice exposed to long-term alcohol use, psilocin dampened the hyperactivity of these neurons, temporarily reducing drinking.

Featured Neurology Neuroscience Pain

·November 7, 2025·5 min read

Nano Tech Helps CBD Quiet Pain at the Source

A new study shows that CBD delivered through a nano-micelle system can cross the blood–brain barrier and produce rapid neuropathic pain relief. The formulation, called CBD-IN, helped mice within 30 minutes and avoided the motor and cognitive side effects often seen with conventional pain drugs.

Brain Cancer Featured Neurology Neuroscience

·October 29, 2025·6 min read

How Chemotherapy Triggers Nerve Damage, and How to Stop It

A new study reveals that chemotherapy-induced nerve pain arises from a stress response in immune cells that triggers inflammation and neurotoxicity. Researchers found that activating a cellular stress sensor called IRE1α causes nerve damage and pain during chemotherapy, but blocking it prevents both in mice.

Featured Neuroscience Psychology

·October 28, 2025·7 min read

Dopamine Boost Makes People More Patient

In one of the largest studies of its kind, researchers found that increasing dopamine levels with L-DOPA made people slightly more willing to wait for larger, delayed rewards—reducing impulsive decisions by about 20%. The study challenges earlier research suggesting that dopamine increases impulsivity, showing instead that it promotes patience and long-term thinking.

Featured Neuroscience Psychology

·October 27, 2025·4 min read

Psychedelics May Rewire Memory Circuits Key to Mental Health

New research suggests that psychedelic drugs may work by strengthening specific brain connections linked to memory and cognition. Scientists found that under psychedelic exposure, neurons in the claustrum—a region dense with psychedelic-sensitive receptors—intensified their communication with the anterior cingulate cortex, a region involved in mood and psychiatric disorders.

Featured Neurology Neuroscience

·October 14, 2025·6 min read

Pregnancy Hormones Show Promise in Treating Progressive MS

Researchers have identified two forms of estrogen, estradiol and estriol, that may reduce inflammation and protect nerve fibers in progressive multiple sclerosis (MS). Using a virus model of the disease, the study found that both hormones lowered spinal cord inflammation, while estradiol significantly preserved the myelin sheath that protects nerve cells.

Brain Cancer Featured Neurology Neuroscience

·October 13, 2025·6 min read

Lymphatic Damage Tied to Chemo Brain Fog

New research reveals that chemotherapy may cause “chemo brain” by damaging the brain’s lymphatic system — the network responsible for clearing waste and supporting immune function. Using mouse models and human-engineered tissues, scientists found that common drugs like docetaxel shrink lymphatic vessels and impair drainage, leading to memory deficits and cognitive decline.

Featured Neurology Neuroscience

·October 9, 2025·8 min read

Compound Could Repair Nerve Damage in Multiple Sclerosis

Researchers have identified two compounds capable of repairing the protective myelin sheath damaged by multiple sclerosis, a major advance toward reversing nerve injury rather than just slowing it. The lead compound, K102, not only promotes remyelination but also balances immune function—key for long-term neurological recovery.

Featured Neurology Neuroscience

·October 7, 2025·6 min read

Tiny Peptide Shows Powerful Brain Healing After Traumatic Injury

A small peptide called CAQK, composed of just four amino acids, has shown remarkable neuroprotective effects in mouse and pig models of traumatic brain injury. When injected intravenously, CAQK travels directly to damaged brain tissue, where it binds to overexpressed proteins and reduces inflammation, cell death, and tissue damage.

Featured Neurology Neuroscience

·October 6, 2025·4 min read

CBD Calms the Inflamed Alzheimer’s Brain

A new study reveals that cannabidiol (CBD) can significantly reduce neuroinflammation associated with Alzheimer’s disease. In experiments using an Alzheimer’s mouse model, researchers found that inhaled CBD lowered the activity of key genes driving inflammation and decreased harmful proinflammatory molecules in the brain.

Featured Neuroscience

·September 30, 2025·6 min read

Targeting the Cerebellum Could Ease Alcohol Withdrawal Symptoms

Researchers have identified the cerebellum as a promising target for easing alcohol withdrawal, the stage of alcohol use disorder that drives many people back to drinking. In mice, withdrawal symptoms were alleviated by calming overactive cerebellar neurons, either through genetic tools or a synthetic compound.

Featured Neurology Neuroscience

·September 26, 2025·3 min read

DMT Shows Promise in Protecting the Brain After Stroke

New research shows that DMT, a natural psychoactive compound found in plants and the human brain, can protect against stroke damage in animal and cell models. Treatment with DMT reduced infarct size, brain swelling, and inflammation, while also repairing blood-brain barrier function.

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neuropharmacology

Psychedelics Calm Stress Circuits to Reduce Alcohol Drinking

Nano Tech Helps CBD Quiet Pain at the Source

How Chemotherapy Triggers Nerve Damage, and How to Stop It

Dopamine Boost Makes People More Patient

Psychedelics May Rewire Memory Circuits Key to Mental Health

Pregnancy Hormones Show Promise in Treating Progressive MS

Lymphatic Damage Tied to Chemo Brain Fog

Compound Could Repair Nerve Damage in Multiple Sclerosis

Tiny Peptide Shows Powerful Brain Healing After Traumatic Injury

CBD Calms the Inflamed Alzheimer’s Brain

Targeting the Cerebellum Could Ease Alcohol Withdrawal Symptoms

DMT Shows Promise in Protecting the Brain After Stroke

Zero-Computational Path to High-Resolution Robotic Touch

Zebrafish Brain Features Mammalian-Like Sensory Sorting

XL20 Crosses Blood-Brain Barrier to Shield ALS Neurons

Humans and Mice Share Identical Brain Wiring for Smell

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