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Common antidepressants interact with opioid med to lessen pain relief

Neuroscience News
SSRI antidepressants, such as Prozac and Paxil, interact with opioid medications to make them less effective at providing relief from chronic pain. Tramadol relies on activation of the CYP2D6 enzyme to control pain, but SSRIs inhibit this enzyme. Researchers suggest prescribing different classes of antidepressants which do not suppress the enzyme may benefit those in need of opioid medications. Alternatively, non-opioid pain killers should be considered for those who can not switch from SSRIs.... Read More...
FeaturedNeurologyNeuroscienceOpen Neuroscience ArticlesPsychology6 min read
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Commonly prescribed drugs could increase the risk of dementia

Neuroscience News
Anticholinergic drugs, commonly prescribed to treat a range of disorders, from Parkinson's disease to bladder conditions, may increase dementia risks. The increased risk was linked to anticholinergic antidepressants, antipsychotics, bladder control, epilepsy and Parkinson's disease medications. There were no increased risks associated with other types of anticholinergics, such as gastrointestinal drugs or antihistamines. ... Read More...
FeaturedNeurologyNeuroscienceOpen Neuroscience Articles7 min read
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‘Ecstasy’ shows promise for post-traumatic stress treatment

Neuroscience News
MDMA shows promise for the treatment of post-traumatic stress disorder. Combining the use of Ecstasy with psychotherapy treatments resulted in a reduction of PTSD symptoms after just one session. 54% of the study participants no longer met the PTSD criteria after two sessions. Patients also reported improvements in depression symptoms.... Read More...
FeaturedNeuroscienceOpen Neuroscience ArticlesPsychology5 min read