Metformin, a drug commonly used to treat diabetes, slows cognitive decline and reduces dementia risk in older people with diabetes. Read More
c9ASO, an investigational ASO drug, targets the TDP-43 protein, reducing its buildup and decreasing neurological decline associated with ALS and FTD. Read More
The popular over-the-counter painkiller acetaminophen increases risk-taking by reducing risk perception, a new study reports. Read More
Ebselen, a Selenium-based drug molecule, and several other novel compounds can change the characteristics of SOD1. The findings could help with the development of new therapeutics for ALS. Read More
Anticholinergic medications, commonly used for conditions including allergies, high blood pressure, Parkinson's disease, and motion sickness, have been linked to an increased risk of cognitive decline and memory problems, especially in those with genetic risk factors for Alzheimer's disease. Read More
Experimental drugs designed to reduce the body's natural production of alpha-ketoglutarate slow tumor growth and increase lifespan in mouse models of DIPG. Read More
CMS121, a synthesized variant of fisetin, a chemical found in fruits and vegetables, improved memory, and slows neurodegeneration in mouse models of Alzheimer's disease. Read More
Pimavanserin substantially reduces symptoms of psychosis and relapse risk for people living with dementia. Read More
Children suffering from a form of autism called ADNP syndrome may benefit from an experimental drug designed to treat Alzheimer's disease. Read More
Spinal cord injuries cause stem cells in the bone marrow to rapidly divide. Following the cell division, the stem cells become trapped in the bone marrow. Read More
Tufts researchers have developed neurotransmitter-lipid hybrids that help transport therapeutic drugs and gene editing proteins across the blood-brain barrier in mice. Read More
Ketamine increases the number of serotonin 1B receptors. Ketamine binds to serotonin 1B receptors, reducing the release of serotonin and increasing the release of dopamine. Read More
