Scientists find promising drug combination against lethal childhood brain cancers
Researchers have discovered a pair of drugs that work together to kill cancer cells and counter genetic mutations that cause diffuse midline gliomas.... Read More...
neuropharmacology
Potential vitamin and Alzheimer’s drug produced in yeast
Researchers were able to produce 0.6 grams of ergothioneine, a natural amino acid that has promising effects on Alzheimer's disease in animal studies, per liter of yeast broth via a small scale fermentation process.... Read More...
Study provides insights on the effects of cannabidiol on severe form of epilepsy
The effect cannabidiol has on Lennox-Gastaut syndrome may be explained by the drug-drug interaction between CBD and anti-seizure medication.... Read More...
Mindfulness meditation enhances positive effects of psilocybin
Mindful meditation enhances the positive effects of a single dose of psilocybin by increasing empathy and reducing egocentricity.... Read More...
Drug combination reverses hypersensitivity to noise
Summary: Treating mouse models of autism with modafinil and EBIO reduced hypersensitivity to noise.Source: MITPeople with autism often experience hypers... Read More...
New therapeutic strategy may help reverse autism behavioral abnormalities
Genetically silencing mTORC2 in mouse models prolonged lifespan, suppressed seizures, increased long-term memory, and reduced autism-like behaviors.... Read More...
Researchers discover potential therapy to treat detrimental effects of marijuana
Prenatal exposure to THC makes dopamine neurons hyperactive and increases the sensitivity to the behavioral effects of the compound during pre-adolescence. This may increase the risk of developing schizophrenia later in life. However, treatment with pregnenolone, a drug under clinical trials for ASD, cannabis use disorder, and schizophrenia, appears to correct the brain abnormalities and behavioral problems associated with prenatal cannabis exposure.... Read More...
Brain mechanisms have potential to block arthritis pain
Researchers discover the amygdala is a critical site of action for pain modulation. An existing compound, LY379268, provides pain-relieving effects and helps to reduce anxiety.... Read More...
Common antidepressant may not reduce depression symptoms, but does reduce anxiety
Sertraline (Zoloft), a commonly prescribed SSRI antidepressant, may not be as effective at treating depression within 6 weeks as previously thought. However, the drug is effective for treating anxiety symptoms. ... Read More...
CBD may alleviate seizures and benefit behaviors in people with neurodevelopmental conditions
CBD, which is a major phytocannabinoid constituent of cannabis, has already shown to have anti-epileptic, anti-anxiety, and anti-psychotic effects. The image is in the public domain.... Read More...
Low-cost blood pressure drug improves brain function in individuals with autism
Propranolol, a common 'beta-blocker' drug used to control blood pressure, could be a promising new treatment for those on the autism spectrum. The medication improved cognitive performance and positively altered the frontal-parietal control network, an area of the brain associated with word and information processing, in those with ASD.... Read More...
Psychedelic drugs: would you accept a prescription? It depends if you’ve tried them before
Numerous studies have linked controlled psychedelics to improvements in mental health conditions such as depression and PTSD. In March, the FDA approved Esketamine as a treatment for depression. However, with much stigma surrounding psychedelics, researchers question how many patients would take psychedelic medications if prescribed to them. According to a new study, 40% of people with no experience of psychedelics would be unlikely to take the prescription due to fears of 'brain damage' or a 'bad trip'.... Read More...