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neuropharmacology

·July 3, 2026·12 min read

XL20 Crosses Blood-Brain Barrier to Shield ALS Neurons

A new study introduces XL20, an experimental small-molecule drug that crosses the blood-brain barrier to selectively block a toxic region on the TDP-43 protein. This precise mechanism halts neuron death and slows muscle wasting in ALS models while leaving the protein's healthy, vital biological functions completely intact.

Featured Neurology Neuroscience Pain

·June 30, 2026·11 min read

Does Melatonin Help Reduce Chronic Pain?

Melatonin can reduce chronic musculoskeletal pain by 9 to 10 points on a 100-point scale. This therapeutic relief matches the efficacy of opioids and NSAIDs while bypassing their severe risks of organ toxicity and addiction, offering a safe, non-dependent adjunct that treats pain and sleep disruption simultaneously.

Featured Genetics Neuroscience

·June 29, 2026·12 min read

Arthritis Drug Found to Reduce Excessive Alcohol Use

An FDA-approved rheumatoid arthritis drug targeting the IL-6 receptor significantly reduces excessive alcohol consumption in alcohol-dependent female mice. The treatment functions by blocking neuroinflammatory pathways that suppress the GABAergic braking system in the central amygdala, a mechanism corroborated by elevated IL-6 expression found in postmortem human AUD brain tissue.

Featured Genetics Neuroscience Visual Neuroscience

·June 22, 2026·11 min read

Lipid Molecule Slows Progressive Retinal Degeneration

Restoring the lipid molecule erucamide via silicon nanoparticles activates retinal myeloid cells via the TMEM19 protein, stabilizing the neurovascular unit and significantly slowing progressive retinal degeneration.

This shows a brain and pills. One half of the brain is red, implying violence.

Featured Neuroscience Psychology

·June 17, 2026·8 min read

Can GLP-1 Medications Blunt the Path to Violence?

GLP-1 receptor agonists, such as Ozempic and Wegovy, may drastically reduce behaviors linked to violence.

Featured Neuroscience Psychology

·June 17, 2026·11 min read

Ingestible Vibrating Capsule Predicts Anorexia Relapse

A new study shows that an ingestible, vibrating capsule can help clinicians determine relapse risk in patients recovering from anorexia nervosa.

Featured Neuroscience

·June 17, 2026·10 min read

Oral Contraceptives Linked to Binge Eating Risk

A new study establishes a link between combined oral contraceptives and increased emotional eating.

Featured Neurology Neuroscience

·June 15, 2026·8 min read

Behavioral Mapping Tames Hallucinations in Alzheimer’s Psychosis

A new report outlines a critical, person-centered framework to manage Alzheimer's-related psychosis without relying on high-risk sedatives.

Featured Neurology Neuroscience

·June 14, 2026·11 min read

Psilocybin Unlocks Lost Memories in an Alzheimer’s Patient

A new study demonstrates that a single dose of psilocybin-containing mushrooms temporarily restored spontaneous speech, motor independence, and urinary continence in an 80-year-old woman with advanced Alzheimer's disease.

Featured Neurology Neuroscience

·June 14, 2026·11 min read

GLP-1s Linked to Low Blood Pressure and Fainting Spikes

Adults taking GLP-1 receptor agonists alongside multiple blood pressure medications experience a significant increase in hypotensive events, including severe dizziness, fainting, and falls.

This shows a person running and a brain.

Featured Neuroscience

·June 13, 2026·8 min read

GLP-1 Therapies Silence Spontaneous Physical Activity

A new study demonstrates that adults managing obesity significantly decrease their physical activity after starting GLP-1 receptor agonist medications.

Featured Neurology Neuroscience

·June 9, 2026·11 min read

Glucosamine Supplement Linked to Accelerated Alzheimer’s Progression

Analyzing 12 years of deidentified patient electronic records using AI, researchers discovered that glucosamine use among individuals with Mild Cognitive Impairment (MCI) is associated with a 25% higher likelihood of progressing to full dementia, alongside a 25% spike in mortality for established Alzheimer’s patients.

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neuropharmacology

XL20 Crosses Blood-Brain Barrier to Shield ALS Neurons

Does Melatonin Help Reduce Chronic Pain?

Arthritis Drug Found to Reduce Excessive Alcohol Use

Lipid Molecule Slows Progressive Retinal Degeneration

Can GLP-1 Medications Blunt the Path to Violence?

Ingestible Vibrating Capsule Predicts Anorexia Relapse

Oral Contraceptives Linked to Binge Eating Risk

Behavioral Mapping Tames Hallucinations in Alzheimer’s Psychosis

Psilocybin Unlocks Lost Memories in an Alzheimer’s Patient

GLP-1s Linked to Low Blood Pressure and Fainting Spikes

GLP-1 Therapies Silence Spontaneous Physical Activity

Glucosamine Supplement Linked to Accelerated Alzheimer’s Progression

Why Cannabis Can Suddenly Trigger Panic

Can an AI Ever Truly Be “Conscious” in the Eyes of Humans?

Comparing Current Appearance to Past Selves Harms Body Image

Optical Illusion Exposes Blind Spot in AI Vision

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