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neuropharamcology

·March 6, 2022·2 min read

How Long-Term Benzodiazepine Use Leads to Cognitive Impairments

Mouse study reveals synaptic loss associated with a daily sleep-inducing dose of diazepam for several weeks leads to cognitive impairments. However, the effect was reversible after discontinuing benzodiazepine use.

This shows a head being erased by a pencil eraser

Featured Neurology Neuroscience

·January 19, 2022·5 min read

Cholesterol Buildup in Brain Presents New Target to Reduce Dementia Risk From Stroke

Cyclodextrin, an FDA-approved drug, reduced cholesterol accumulation from broken down brain cells and inflammation in animal models. The findings point to a potential new therapy to reduce dementia following a stroke.

Featured Neuroscience

·September 27, 2021·5 min read

Withdrawal From Psychostimulants Restructures Functional Architecture of Brain

Withdrawal from psychostimulants including methamphetamines, cocaine, and nicotine, produced restructuring of brain regions and major increases in functional connectivity, a new mouse study reveals.

Featured Neuroscience Psychology

·April 28, 2021·4 min read

A Psychedelic-Like Drug Without the Hallucinogenic Side Effects

PsychLight, a newly developed genetically encoded fluorescent sensor, helped researchers identify a psychedelic compound that acts on beneficial neural pathways to treat psychiatric disorders without the hallucinogenic effect.

Featured Neurology Neuroscience Pain

·April 25, 2021·6 min read

Research Shows Pain Relieving Effects of CBD

CBD does not appear to reduce experimental pain intensity but does make the experience of pain less unpleasant.

This is a stick and ball model of dopamine

Featured Neurology Open Neuroscience Articles

·July 15, 2020·5 min read

Dopamine Therapy Improves Cognitive Function in Alzheimer’s

Rotigotine, a drug that acts on dopamine transmission, improves cognitive function in patients with mild-to-moderate Alzheimer's disease. While the drug did not help improve memory, it did improve executive function in the frontal lobe and positively impacted the ability of patients to perform activities of daily living.

Featured Neuroscience

·April 17, 2020·3 min read

New nanocarrier drug delivery technology crosses the blood-brain barrier

Researchers have developed a cyclic peptide that can enhance blood-brain barrier penetration.

Featured Neurology Neuroscience Open Neuroscience Articles

·March 11, 2020·4 min read

Common muscle relaxant given via nose shows potential to treat Alzheimer’s

Dantrolene, a common muscle relaxant, shows promise in the treatment of Alzheimer's disease. Mice administered the drug intranasally had higher concentrations of the medicine in their brains, and for longer periods, than those who received it orally. The drug has been shown to help inhibit or slow the progression of several neurodegenerative diseases.

Featured Neurology Neuroscience

·January 16, 2020·3 min read

Antipsychotics associated with increased risk of head & brain injuries in persons with Alzheimer’s disease

Alzheimer's patients who used antipsychotics had a 29% increased risk of head injury and a 22% higher risk of TBI compared to others with the neurodegenerative disease who did not use the medications.

Featured Neurology Neuroscience

·May 21, 2019·4 min read

CBD clinical trial results on seizure frequency in dogs ‘encouraging’

Dogs with epilepsy who received cannabidiol as part of a clinical trial had a reduction in the frequency of seizures.

Featured Neuroscience Open Neuroscience Articles Psychology

·July 19, 2018·5 min read

ADHD Drugs Do Not Improve Cognition in Healthy College Students

Researchers report, contrary to popular belief, Adderall and other ADHD drugs do not improve cognition in healthy college students. Instead, they may impair cognitive function.

Featured Neurology

·July 2, 2018·7 min read

Experimental Drug Stops Parkinson’s Progression: Mouse Study

A newly developed experimental drug, that contains similar compounds to those in diabetes medications, slows the progression of Parkinson's in mouse models of the disease, researchers report.

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neuropharamcology

How Long-Term Benzodiazepine Use Leads to Cognitive Impairments

Cholesterol Buildup in Brain Presents New Target to Reduce Dementia Risk From Stroke

Withdrawal From Psychostimulants Restructures Functional Architecture of Brain

A Psychedelic-Like Drug Without the Hallucinogenic Side Effects

Research Shows Pain Relieving Effects of CBD

Dopamine Therapy Improves Cognitive Function in Alzheimer’s

New nanocarrier drug delivery technology crosses the blood-brain barrier

Common muscle relaxant given via nose shows potential to treat Alzheimer’s

Antipsychotics associated with increased risk of head & brain injuries in persons with Alzheimer’s disease

CBD clinical trial results on seizure frequency in dogs ‘encouraging’

ADHD Drugs Do Not Improve Cognition in Healthy College Students

Experimental Drug Stops Parkinson’s Progression: Mouse Study

Fumes from Indoor Cooking Fuels Linked to Developmental Delays

Mood Dips During Pill Pause

Visual Recognition Memory: Familiarity Decoded by Brief Spikes

HSN Neuron Unravels Behavior Mysteries

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