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Neurology

·December 18, 2024·4 min read

Circadian Clock Influences Inflammation and Disease

New research reveals how the body’s circadian clock regulates macrophage activity, influencing immune system inflammation throughout the day. Activation of the NLRP3 inflammasome, a key component in the immune response, peaks during the morning when macrophages are most efficient.

Featured Genetics Neurology Neuroscience

·December 17, 2024·3 min read

Neural Stem Cell Transplants Show Promise for Spinal Injuries

A Phase I clinical trial has demonstrated the long-term safety of neural stem cell transplantation for chronic spinal cord injuries. Researchers followed four patients for five years, with two showing sustained neurological improvements, including better motor function and sensory responses.

Featured Neurology Neuroscience

·December 16, 2024·4 min read

Accurate Parkinson’s Detection via Emotional Brain Responses

A new study has achieved near-perfect accuracy in detecting Parkinson's disease by analyzing brain responses to emotional stimuli using EEG and AI. Researchers found that Parkinson's patients process emotions differently, struggling with recognizing fear, disgust, and surprise and focusing more on emotional intensity than valence.

This shows people reading in front of a TV and a brain.

Featured Neurology Neuroscience

·December 16, 2024·5 min read

Some Sedentary Activities Are Good For Brain Health

New research highlights that some sedentary activities, like reading or crafting, are better for brain health than others, such as watching TV or gaming. A study of 397 older adults found that mentally stimulating and socially engaging activities support memory and thinking abilities, while passive screen time is linked to cognitive decline.

Brain Cancer Featured Neurology Neuroscience

·December 12, 2024·8 min read

Glioblastoma Syncs With the Body’s Internal Clock

Glioblastoma, an aggressive brain cancer, syncs its internal clock to the host’s circadian rhythms, leveraging daily hormone cycles for growth. Blocking these signals slowed tumor progression in mice and revealed that the timing of treatments like dexamethasone (DEX) critically influences outcomes.

Featured Neurology Neuroscience Neuroscience Videos

·December 10, 2024·5 min read

Diets That Reduce Brain Iron May Delay Cognitive Decline

New research suggests that certain nutrients may lower iron buildup in the brain, a factor linked to cognitive decline in aging. Excess non-heme iron, which accumulates over time, contributes to oxidative stress and can impair memory and executive function.

Featured Neurology Neuroscience

·December 10, 2024·5 min read

Skull Marrow and Sinuses Hold the Key to Brain-Body Immune Link

The dural sinuses and skull bone marrow serve as key communication hubs between the brain's central immune system and the body's peripheral immune system. These regions may act as "traffic lights," allowing immune signals to flow between the brain and body, challenging the traditional view of the blood-brain barrier as an absolute divide.

Featured Neurology Neuroscience Pain

·December 9, 2024·3 min read

New Target for Chronic Pain Identified

Researchers have identified a natural substance, hederagenin, that blocks the NPFFR1 receptor, a protein involved in pain perception in the brain and spinal cord. NPFFR1 has long been a challenging target due to its similarities to related receptors, but advanced screening and computer modeling revealed its unique binding mode.

Brain Cancer Featured Neurology Neuroscience

·December 9, 2024·6 min read

Lab-Grown Tumor Models Mirror Glioblastoma Treatment Response

Glioblastoma organoids, lab-grown replicas of a patient’s tumor, accurately predict how the tumor responds to CAR T cell therapy. This breakthrough allows real-time testing of therapies, showing that responses in the organoid closely mirror those in the patient.

Featured Neurology Neuroscience Pain

·December 9, 2024·4 min read

Healthy Diet Linked to Reduced Chronic Pain

Chronic pain, affecting millions worldwide, may be alleviated by adopting a healthy diet, according to new research. A new study found that eating more vegetables, fruits, grains, lean proteins, and dairy was linked to less pain, especially among women, regardless of body weight.

Brain Cancer Featured Neurology Neuroscience

·December 6, 2024·7 min read

Targeted Immune Cells Destroy Brain Tumors

Researchers have created a "molecular GPS" to guide immune cells directly to the brain, enabling precise targeting of tumors like glioblastoma. These cells use a unique protein code to navigate and attack cancer while sparing healthy tissue, offering a safer alternative to traditional treatments. In mice, this technology successfully cleared tumors, prevented recurrences, and reduced brain inflammation in models of multiple sclerosis.

This shows nerve growth factor receptor TrkA.

Featured Neurology Neuroscience Pain

·December 6, 2024·7 min read

A Novel Pain Signaling Complex Discovered

Researchers identified a new receptor, neuropilin-1 (NRP1), which collaborates with a known receptor to regulate pain signaling from nerve growth factor. Unlike traditional signaling receptors, NRP1 acts as a co-receptor to enhance pain signals without directly transmitting them. The study showed how blocking NRP1 or disrupting its interaction with nerve growth factor could offer novel approaches to pain treatment.

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Neurology

Circadian Clock Influences Inflammation and Disease

Neural Stem Cell Transplants Show Promise for Spinal Injuries

Accurate Parkinson’s Detection via Emotional Brain Responses

Some Sedentary Activities Are Good For Brain Health

Glioblastoma Syncs With the Body’s Internal Clock

Diets That Reduce Brain Iron May Delay Cognitive Decline

Skull Marrow and Sinuses Hold the Key to Brain-Body Immune Link

New Target for Chronic Pain Identified

Lab-Grown Tumor Models Mirror Glioblastoma Treatment Response

Healthy Diet Linked to Reduced Chronic Pain

Targeted Immune Cells Destroy Brain Tumors

A Novel Pain Signaling Complex Discovered

AI Body Gap: Why Robots Need “Internal Feelings” to be Safe

Wetware AI: Living Brain Cells Trained to Run Chaos Math

Mapping the Brain’s Internal Stopwatch

Individual Cone Cells Create Our Sharpest Sight

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