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Featured Genetics Neurology Neuroscience

·August 11, 2025·5 min read

Reshaping Nuclear Speckles Could Halt Alzheimer’s

A groundbreaking study reveals that reshaping nuclear speckles — tiny structures inside cell nuclei that regulate protein maintenance — could be a novel way to treat proteinopathies like Alzheimer’s, Parkinson’s, and prion diseases. Researchers found that pyrvinium pamoate, an existing FDA-approved drug, alters the surface tension of nuclear speckles, making them less round and more effective at supporting proteostasis.

This shows healthy microglia and neurons.

Featured Neurology Neuroscience

·August 11, 2025·8 min read

Microglia Transplant Restores Function in Degenerative Brain Disease

Scientists have developed a targeted brain cell transplant that could transform treatment for Tay-Sachs and Sandhoff diseases. By depleting diseased microglia and replacing them with healthy donor precursor cells, researchers restored crucial enzyme function in the brain and dramatically extended lifespan in mice.

Featured Neurology Neuroscience

·August 9, 2025·4 min read

Natural Compound Combo Restores Aging Brain Cells

Scientists have identified a natural compound combination that reverses aging-related brain cell decline and removes harmful Alzheimer’s-linked proteins. The treatment, combining nicotinamide (vitamin B3) and the green tea antioxidant epigallocatechin gallate, restores guanosine triphosphate (GTP) levels—critical for neuronal energy and protein cleanup.

This shows an older man on an exercise bike in a hospital. A nurse is at his side. On the cycle is a monitor with a brain game.

Featured Neurology Neuroscience

·August 3, 2025·7 min read

Cycling Boosts Brain Function in Parkinson’s Disease

A new study reveals that long-term adaptive cycling can measurably reshape brain signals in people with Parkinson’s Disease, offering clues into how exercise relieves motor symptoms. Researchers used deep brain stimulation (DBS) implants to track neural activity before and after 12 sessions of dynamic cycling.

This shows a person with their signal cord highlighted. In the background are people with various mobility devices.

Featured Neurology Neuroscience

·August 1, 2025·6 min read

Signs of MS Emerge 15 Years Before Diagnosis

A large-scale analysis of health records reveals that subtle signs of multiple sclerosis (MS) may appear more than a decade before diagnosis. People who eventually develop MS began increasing healthcare visits—especially for general symptoms like fatigue, pain, and anxiety—15 years before neurologists identified their first demyelinating event.

This shows an older woman looking through a photo album with her caregiver.

Featured Neurology Neuroscience

·July 30, 2025·5 min read

Dementia Often Goes Undiagnosed for Over 3 Years

A global analysis has revealed that people with dementia wait an average of 3.5 years after symptom onset before receiving a diagnosis. The delay is even longer—about 4.1 years—for early-onset dementia, with younger patients and those with frontotemporal dementia facing the greatest lags.

This shows a person holding their stomach in pain, surrounded by COVID molecules, reflecting how COVID has impacted the gut-brain axis health.

Featured Neurology Neuroscience

·July 30, 2025·4 min read

Post-COVID Spike in Gut-Brain Disorders

A major international study confirms that disorders of gut-brain interaction have increased significantly since the COVID-19 pandemic. Using consistent diagnostic tools across 2017 and 2023 populations, researchers found notable surges in IBS and functional dyspepsia.

This shows a large viral cell and DNA with a researcher analyzing data in the background.

Featured Genetics Neurology Neuroscience

·July 29, 2025·4 min read

DNA Reveals Multiple Sclerosis Risk Before Symptoms Begin

Researchers are launching a groundbreaking study to investigate how genetics and the Epstein-Barr virus may work together to trigger multiple sclerosis (MS). Using a method called "recall by genotype," the team will compare biological traits in people with high and low genetic risk—long before symptoms arise.

Featured Neurology Neuroscience

·July 25, 2025·3 min read

Microglia May Hold Key to Slowing Alzheimer’s Progression

Alzheimer’s disease is marked by toxic amyloid-beta protein clumps, but some people seem naturally protected. A new study reveals that a receptor called ADGRG1 enables immune cells called microglia to effectively clear these harmful plaques.

$This shows a brain.$

Featured Neurology Neuroscience

·July 24, 2025·6 min read

Math Models Reveal Why Alzheimer’s Damages Some Brain Areas More

Alzheimer’s disease spreads unevenly through the brain, and new mathematical modeling may help explain why. Researchers developed a network diffusion model that simulates how tau protein accumulates and spreads, identifying genes that either increase or reduce vulnerability.

Featured Neuroscience Psychology

·July 22, 2025·4 min read

COVID Stress May Have Aged Brains Faster

Living through the Covid-19 pandemic may have accelerated brain ageing, even in people who were never infected, a new study finds. Brain scans of nearly 1,000 adults showed older, male, and disadvantaged individuals were most affected.

Featured Neurology Neuroscience

·July 22, 2025·6 min read

Synaptic Tau and Astrocytes Drive PSP Progression

ew research uncovers how tau pathology spreads and damages synapses in progressive supranuclear palsy (PSP). Using human postmortem tissue and live brain slice models, scientists showed tau accumulates in both pre- and postsynaptic terminals, likely propagating neuron-to-neuron.