neurodegenerative diseases

This shows a brain

Frontotemporal dementia is associated with alterations in immune system function

Researchers discovered increased inflammatory activity in a subgroup of patients with frontotemporal dementia. The increased inflammation was indicated by elevated levels of cytokines known to increase inflammatory response and decreased levels of IL-10, which reduces inflammation. The inflammation was associated with Parkinsonism's symptoms and rapid cognitive and functional decline. The study also revealed patients with FTD are less likely to develop cancer.... Read More...
This shows a man sleeping

Rare sleep disorder common among veterans with PTSD

21% of veterans who experience PTSD or traumatic brain injury suffer from a rare sleep condition that affects less than 1% of the general population. The condition, REM sleep behavior disorder (RBD), is characterized by an impairment of sleep-related muscle paralysis, causing people to act out dreams during REM sleep. The uncontrolled actions often cause harm to the sufferer of their partners. ... Read More...
This shows stills from the video

Study pinpoints Alzheimer’s plaque emergence early and deep in the brain

Researchers use SWITCH technology to label amyloid plaques in mouse models of Alzheimer's disease so they could be imaged in fine detail at different ages. They were consistently able to see the plaques first emerged in deep brain structures and tracked circuits, such as the Papez memory circuit, to spread throughout the brain as the animal aged.... Read More...
This shows a person walking

Walking patterns can identify dementia type

People with two common types of dementia, Lewy body dementia, and Alzheimer's disease, have unique walking patterns. The gait type signals subtle differences between the two disorders. Those with Lew body dementia change their steps more, varying the step time and length. They also display more asymmetry in movement compared to those with Alzheimer's disease. Researchers say gait could be a clinical biomarker for dementia subtypes.... Read More...