FeaturedNeurologyNeuroscience·May 21, 2020ALS biomarker found in children’s teethResearchers have identified a new, early biomarker for amyotrophic lateral sclerosis (ALS) on the teeth of children. Patients who were diagnosed with ALS in adulthood showed signs of dysregulation uptake of a mixture of essential elements, including zinc, copper, lead, and tin, on their teeth. The study is the first to show clear signatures at birth and within the first decade of life for ALS. Read More
FeaturedNeurologyNeuroscience·May 20, 2020Link between diesel exhaust and risk of Parkinson’s discoveredResearchers have uncovered the process by which air pollution can damage brain cells, leading to an increased risk of Parkinson's disease. Chemicals found in diesel fuel reduced autophagic flux, which is a major pathway implicated in neurodegeneration. Read More
FeaturedGeneticsNeurologyNeuroscience·May 19, 2020Animal study shows human brain cells repair damage in multiple sclerosisHuman iPSCs transplanted into animal models of multiple sclerosis help repair cell damage and restore function. Read More
FeaturedNeurologyNeuroscienceOpen Neuroscience Articles·May 16, 2020Certain Memory Complaints Predict Future DementiaSubjective cognitive complaints may be the earliest detectable stages of preclinical dementia. Read More
FeaturedNeurologyNeuroscience·May 15, 2020Gut microbiome influences ALS outcomesStudy reveals a new gut-brain connection in amyotrophic lateral sclerosis (ALS). The gut microbiome could influence the severity of the neurodegenerative disease. Altering the bacteria in the gut may prevent or improve symptoms of ALS. Read More
FeaturedNeurologyNeuroscienceOpen Neuroscience Articles·May 14, 2020Retinal texture could provide early biomarker of Alzheimer’s diseaseThe topmost layer of neurons in the retina of mouse models of Alzheimer's disease exhibits textural changes. The findings could be a new biomarker for Alzheimer's disease. Read More
FeaturedNeurologyNeuroscience·May 11, 2020Resilience to ALS due to synaptic safety mechanismStudy reveals a self-corrective mechanism within synapses that is activated by neurodegeneration and slows disease progression in animal models of ALS. Read More
FeaturedNeurologyNeuroscience·May 5, 2020New evidence that higher caffeine and urate levels are protective against Parkinson’sCaffeine and urate have been associated with a reduced risk of idiopathic Parkinson's disease. Researchers noted a lower caffeine intake in idiopathic Parkinson's patients. Increasing caffeine consumption was linked to decreased odds of being diagnosed with Parkinson's. Lower levels of blood urate were also associated with an increased risk of Parkinson's disease. Read More
FeaturedNeurologyNeuroscienceOpen Neuroscience Articles·May 5, 2020Flavonoid-rich berries, fruits and tea may have a protective benefit against Alzheimer’sConsuming a flavonoid-rich diet could help combat the development and progression of Alzheimer's disease for those with risk factors. Low intake of specific flavonoids, especially anthocyanins, which are found in blueberries and strawberries, was associated with a four-fold risk of developing Alzheimer's. Read More
artificial intelligencedeep learningFeaturedmachine learningNeurologyNeuroscienceneurotechOpen Neuroscience Articles·May 4, 2020Artificial intelligence algorithm can accurately predict risk and diagnose Alzheimer’s diseaseCombining brain imaging data with a new machine learning algorithm, researchers can accurately predict the risk and determine a diagnosis for Alzheimer's disease. Read More
FeaturedNeurologyNeuroscienceOpen Neuroscience Articles·April 30, 2020Researchers unravel protein mystery of three brain diseasesResearchers have identified two different shapes of alpha-synuclein associated with multiple systems atrophy (MSA) and Lewy body dementia. The structure of the protein is helical in MSA, causing the symptoms to occur more quickly and aggressively. In Lewy body dementia, the protein takes on a cylindrical form. Read More
FeaturedGeneticsNeurologyNeuroscience·April 29, 2020APOE4 triggers early breakdowns in the blood-brain barrierAPOE4, a gene implicated as a risk factor for Alzheimer's disease, triggers leaks in the blood-brain barrier. The damage to capillaries APOE4 causes correlates with increased levels of cyclophilin, a protein that causes the inflammation that is a signature of early Alzheimer's. Read More
