A new test that measures dopamine levels in biological fluids could help with the detection of depression, Parkinson's disease, and other disordered marked by abnormal dopamine levels.
High-fat diets promote early inflammatory responses in the brain via an immune pathway associated with diabetes and neurodegenerative diseases. The findings suggest a link between metabolic dysfunction and cognitive impairment.
A new study aims to investigate the interaction between the digestive and nervous systems, or the gut-brain axis, to discover more about the links between digestive health and neurodegenerative diseases.
Using CRISPR gene editing to directly target RNA, researchers eliminated toxic protein buildup associated with Huntington's disease while not disrupting other human genes.
Gene usage in the brains of those who suffered severe COVID-19 infections was similar to that observed in the aging brain. Researchers say COVID-19 is associated with molecular signatures of brain aging.
Researchers identified two genes that respond to age-related iron accumulation in the substantia nigra. Knockdown of these genes results in severely impairing the cellular tolerance for iron toxicity.
Riluzole, an FDA-approved drug to treat ALS, can, in part, correct the molecular cause of some leukodystrophies.
Findings could have implications for new avenues of research for a range of neurodegenerative diseases including ALS and Alzheimer's.
91% of people say they would definitely like to take a simple test to analyze their risks of developing neurological disorders if they were available.
The signals that originate in the cells of the blood-brain barrier also play a direct role in controlling what happens to the neurons the barrier is protecting.
A new study sheds light on the genetic causes of a range of neurodegenerative disorders, including ALS, Parkinson's disease, and Huntington's disease, and determines factors that impact the age of onset as well as disease severity.
Synthesizing a human embryo from stem cells and using gene editing to insert the Huntingtin gene, researchers found the mutation affected the size of germ layers compared to the control embryos. Findings suggest Huntington's disease may be a neurodevelopmental disorder that presents as a neurodegenerative disease later
