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nanoparticles

·February 18, 2025·5 min read

Nanoparticles Deliver mRNA to the Brain, Bypassing Blood-Brain Barrier

Scientists have developed a lipid nanoparticle system that enables mRNA to cross the blood-brain barrier, a long-standing challenge in neuroscience. In studies using mice and human brain tissue, these nanoparticles successfully delivered therapeutic mRNA, opening doors for potential treatments for neurological diseases like Alzheimer’s, ALS, and brain cancer.

Brain Cancer Featured Neurology Neuroscience

·May 6, 2024·6 min read

Nanoparticles Penetrate Blood-Brain Barrier to Treat Cancer

Researchers developed a novel nanoparticle that can cross the blood-brain barrier to target both primary breast tumors and brain metastases simultaneously. This dual-action approach utilizes a biodegradable polymer loaded with two prodrugs targeting cancer cell mitochondria.

Featured Genetics Neurology Neuroscience

·January 20, 2023·4 min read

New Nanoparticles Deliver Therapy Brain-Wide and Edit Alzheimer’s Gene

Researchers have developed a new family of nano-scale capsules capable of carrying CRISPR gene editing tools to different organs of the body before harmlessly dissolving. The capsules were able to enter the brains of mice and successfully edit a gene associated with Alzheimer's disease.

This shows the nanoparticles entering the retina

Featured Genetics Neuroscience Visual Neuroscience

·January 12, 2023·3 min read

A Key Step Toward New Treatment for Hereditary Blindness

Using animal models, researchers demonstrate a potentially effective approach to treating blindness associated with genetic conditions by using mRNA and lipid nanoparticles.

This is a cartoon of a smiling neuron surrounded by nano particles

Featured Neurology Neuroscience

·February 28, 2021·2 min read

Nanoparticles Help Untangle Alzheimer’s Disease Amyloid Beta Plaques

Amyloid plaques can cling to newly developed bowl-shaped nanoparticles. The findings provide a new way to study the Alzheimer's related plaques and provides novel treatment options for dementia.

Featured Neurology Neuroscience

·January 1, 2021·5 min read

Nanoparticle Drug-Delivery System Developed to Treat Brain Disorders

A new nanoparticle drug-delivery system resulted in unprecedented siRNA penetration across the intact blood-brain barrier. Researchers say the system could help doctors to treat secondary injuries associated with TBI that can result in Alzheimer's and other neurodegenerative disorders.

Featured Neuroscience Open Neuroscience Articles

·June 3, 2018·6 min read

AI Method Could Speed Up Development of Specialized Nanoparticles

A new artificial intelligence technique could speed up complex physics simulations and help create multilayered nanoparticles, researchers say.

Brain Cancer Featured Neurology Open Neuroscience Articles

·May 24, 2018·5 min read

Tiny Particles Could Help Fight Brain Cancer

Researchers at MIT have developed a new drug delivering nanoparticle that is able to cross the blood-brain barrier. The nanoparticles carry two different drugs that can help shrink tumors and prevent them from growing back.

Image shows a diagram of the nanoparticles.

Featured Neuroscience

·January 23, 2017·7 min read

Noninvasive Ultrasound Pulses Used to Precisely Tweak Rat Brain Activity

A new study outlines how researchers have been able to deliver concentrated amounts of drugs directly into the brains of rats by using ultrasound.

Featured Neurology Neuroscience Neuroscience Videos

·September 6, 2016·2 min read

Toxic Air Pollution Nanoparticles Found in the Human Brain

Researchers report they have discovered tiny magnetic nanoparticles from air pollution lodged in the human brain. They believe these nanoparticles could contribute to some cases of Alzheimer's.

Featured Neuroscience

·November 17, 2015·4 min read

Luminescent Nanoparticles Image Brain Function

Researchers are on pace to develop the next generation of functional materials that could enable the mapping of the complex neural connections in the brain.