The way zebrafish respond to repeated exposure and withdrawal from nicotine mirrors more complex human responses during withdrawal.
Common green apple flavorant farnesene enhances nicotine reward in mouse models. The flavorant is also rewarding on its own. Researchers say with or without nicotine, flavored vapes, especially those containing farnesene, pose potential neurological risks, including addiction.
According to a new study, nicotine reduces dorsal striatal output, underlying the urge to smoke and making it difficult to quite the addiction.
Researchers report alpha 7 nicotinic acetylcholine receptors enhance communication between the hippocampus and frontal cortex, where as a4b7 nicotinic receptors decrease the communication. The findings may have implications for the way stimulation of acetylcholine can be used to treat dementia.
A new study reports coupling menthol with nicotine acts to desensitize receptors in the lungs and airways.