Researchers have identified two different shapes of alpha-synuclein associated with multiple systems atrophy (MSA) and Lewy body dementia. The structure of the protein is helical in MSA, causing the symptoms to occur more quickly and aggressively. In Lewy body dementia, the protein takes on a cylindrical form.
Researchers have identified how specific brain areas change over time in patients with Parkinson's disease.
A new study links a lack of SMG1 to protein aggregates associated with Parkinson's disease and other neurodegenerative diseases.