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Multiple Sclerosis

Featured Genetics Neurology Neuroscience

·October 4, 2019·4 min read

Targeting certain rogue T cells prevents and reverses multiple sclerosis: Mouse study

TH17 cells produced increased amounts of SerpinB1, a protein implicated in multiple sclerosis symptoms. SerpinB1 cells were identified with antibodies targeting the CXCR6 surface protein. Using monoclonal antibodies to target CXCR6, the cells disappeared significantly, and the mice primed to develop MS did not develop the disease.

Featured Neurology Neuroscience

·August 22, 2019·3 min read

Treating inflammation with inflammation

Ter119, an inflammatory antibody, has the potential to treat inflammation caused by autoimmune diseases, according to the findings of a new rodent study.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·August 21, 2019·4 min read

X chromosome gene may explain why women are more prone to autoimmune diseases

Kdm6a, a gene on the X chromosome appears to be associated with the development of autoimmune diseases, such as Multiple Sclerosis. The gene is expressed more in the immune cells of females than males. When Kdm6a was deleted in mouse models of MS, the animals had improved symptoms and reduced inflammation. The findings shed light on why women are more prone to autoimmune diseases than males.

Featured Neurology Neuroscience Open Neuroscience Articles

·August 18, 2019·4 min read

Vegetable-rich Wahls diet lowers fatigue in multiple sclerosis patients by raising good cholesterol

Eating a diet high in vegetables can help reduce symptoms of fatigue in those with progressive multiple sclerosis.

Featured Genetics Neuroscience

·August 14, 2019·3 min read

Scientists reverse aging process in rat brain stem cells

Removing Piezo1 from the surface of aged brain stem cells caused the cells to become rejuvenated and regain their normal regenerative function.

Featured Neurology Neuroscience

·August 12, 2019·4 min read

Smoldering spots in the brain may signal severe MS

Dark rimmed spots on the brain that represent ongoing inflammation, known as chronic active lesions, may be a hallmark of a more aggressive and debilitating form of multiple sclerosis. The findings provide a new biomarker for diagnosing the neurological disorder.

This shows brain slices with a glioblastoma tumor

Brain Cancer Featured Neurology Neuroscience

·August 8, 2019·5 min read

Adding MS drug to targeted cancer therapy may improve glioblastoma outcomes

Teriflunomide, a drug commonly used to treat multiple sclerosis, shows promise for the treatment of glioblastoma when coupled with targeted cancer therapies.

Featured Neurology Neuroscience

·July 31, 2019·4 min read

Vaccinations not a risk factor for multiple sclerosis

A study of over 200,000 people found no evidence that vaccinations increase the risk of developing multiple sclerosis, or the onset of an initial MS episode.

This shows a woman walking with a walking stick

Featured Genetics Neurology Neuroscience

·July 23, 2019·3 min read

Fingerprint of Multiple Sclerosis Immune Cells Identified

T helper cells in the blood of patients with multiple sclerosis infiltrate the central nervous system, causing inflammation and neural damage.

Featured Neurology Neuroscience

·July 17, 2019·4 min read

Study pinpoints cell types affected in brains of multiple sclerosis patients

Projection neurons have been implicated in the progression of multiple sclerosis. A new study reports projection neurons are damaged by immune cells. This damage could contribute to both atrophy and cognitive changes associated with the disease.

Featured Neurology Neuroscience Open Neuroscience Articles

·July 16, 2019·3 min read

Gut microbes protect against neurologic damage from viral infections

A healthy and diverse microbiome is essential for quickly clearing viral infections in the nervous system to prevent risks associated with multiple sclerosis. Mice with lower gut bacteria had weaker immune responses and were unable to eliminate viruses, leading to worsening paralysis. Those treated with antibiotics before infection had fewer microglia.

Featured Genetics Neurology Neuroscience

·July 15, 2019·5 min read

Differences in MS patients’ cerebrospinal fluid may be key to drugs that halt progression

Ceramide exposure impairs the ability for neurons to make energy by directly damaging mitochondria. Additionally, ceramides force neurons to rapidly uptake glucose in order to provide cellular energy.