Researchers report they have successfully developed 'mini-brains' made up of the many neurons and cells in the human brain. The mini brains could allow for better research and reduce the need for animal testing.
Decreasing the amount of Reelin significantly protected against disease symptoms and promoted recovery in symptomatic animal models of multiple sclerosis. Reelin levels appear to correlate with MS severity and stages. Researchers report lowering levels of the protein could be a potential avenue of treatment for the autoimmune disorder.
Researchers take a deeper look at synesthesia, revealing the condition could be linked to some autoimmune diseases. The paper also reports synesthetes have better memory and are more creative than those without the disorder.
12 genes associated with familial multiple sclerosis have been identified. The findings provide a molecular rationale for the chronic inflammation, demyelination and neurodegeneration associated with MS. Identifying new genetic targets could help with the development of novel treatments to prevent multiple sclerosis in those with a genetic risk.
For the first time ever, stem cells from umbilical cords have been converted into other types of cells, which may...
According to a new study, an insufficient amount of good bacteria could have a direct link to MS.
Renewed, thin myelin sheaths are sufficient to help restore nervous system impairments in diseases like multiple sclerosis, a new study in PNAS reports.
A global knockout of the thrombin receptor PAR1 accelerates myelin development. The findings could help with the development of treatments for diseases associated with demyelination, like multiple sclerosis.
Injecting extracellular vesicles from healthy mice into mice that had an MS-like disease resulted in the development of a relapse-remitting disease and active CD8+ cells, similar to that seen in human patients with multiple sclerosis. Examining the EVs in mice and humans with MS, researchers identified they contained fibrinogen, a protein normally associated with blood clotting and wound healing. According to researchers, the EVs with fibrinogen appear to activate the CD8+ immune cells. The findings could help with the development of new treatments for RRMS.