Being bilingual may protect from cognitive decline in multiple sclerosis
Bilingual multiple sclerosis patients score better than those who are monolingual in cognitive tests.... Read More...
Multiple Sclerosis
A molecular switch for repairing central nervous system disorders
A global knockout of the thrombin receptor PAR1 accelerates myelin development. The findings could help with the development of treatments for diseases associated with demyelination, like multiple sclerosis.... Read More...
The gut may be involved in the development of multiple sclerosis
Increased levels of Smad7 in T-cells is linked to multiple sclerosis-like symptoms in mice. In the intestines, the T-cells were more frequently activated and migrated to the central nervous system, where they triggered inflammation. Similar activation was seen in human patients with multiple sclerosis. The findings provide further evidence that multiple sclerosis may start in the intestines and spread via the CNS.... Read More...
Multiple sclerosis linked to variant of common herpes virus
Researchers link the Human Herpes Virus 6A to the development of multiple sclerosis.... Read More...
Gut instincts: Researchers discover first clues on how gut health influences brain health
Mice bred to be germ-free, and those treated with antibiotics showed a significant reduction in the ability to learn that a threatening danger was no longer present. Sequencing the RNA of microglia in the brains of the animals reveals altered gene expression in the immune cells, which play a role in remodeling how neurons connect during the learning process. Restoring the gut microbiota reverse the learning problems.... Read More...
Stem cell transplant reverses disabling MS-like disease
Hematopoietic stem cell transplantation reversed neuromyelitis optica. Five years following transplantation, only 2 of twelve patients had relapsed.... Read More...
Surprise contributor to multiple sclerosis identified
Oligodendrocyte progenitor cells (OPCs) actively contribute to neuroinflammation associated with multiple sclerosis.... Read More...
Targeting certain rogue T cells prevents and reverses multiple sclerosis: Mouse study
TH17 cells produced increased amounts of SerpinB1, a protein implicated in multiple sclerosis symptoms. SerpinB1 cells were identified with antibodies targeting the CXCR6 surface protein. Using monoclonal antibodies to target CXCR6, the cells disappeared significantly, and the mice primed to develop MS did not develop the disease.... Read More...
Treating inflammation with inflammation
Ter119, an inflammatory antibody, has the potential to treat inflammation caused by autoimmune diseases, according to the findings of a new rodent study.... Read More...
X chromosome gene may explain why women are more prone to autoimmune diseases
Kdm6a, a gene on the X chromosome appears to be associated with the development of autoimmune diseases, such as Multiple Sclerosis. The gene is expressed more in the immune cells of females than males. When Kdm6a was deleted in mouse models of MS, the animals had improved symptoms and reduced inflammation. The findings shed light on why women are more prone to autoimmune diseases than males.... Read More...
Vegetable-rich Wahls diet lowers fatigue in multiple sclerosis patients by raising good cholesterol
Eating a diet high in vegetables can help reduce symptoms of fatigue in those with progressive multiple sclerosis. ... Read More...
Scientists reverse aging process in rat brain stem cells
Removing Piezo1 from the surface of aged brain stem cells caused the cells to become rejuvenated and regain their normal regenerative function.... Read More...