Piezo1 limits the potential of regulatory T cells (Treg) to mitigate autoimmune neuroinflammation. Inhibiting Piezo1 could lead to new treatments for autoimmune disorders like multiple sclerosis.
Scars and lesions on the brain and spinal cord offer clues as to why progressive disability occurs in patients with multiple sclerosis.
A diet rich in foods containing isoflavone, a plant-based compound found in legumes, chickpeas, and peanuts, that resembles estrogen, protects against multiple sclerosis symptoms in mouse models.
More frequent hospital and doctor's office visits in the years leading up to multiple sclerosis diagnosis with early MS type symptoms are usually associated with a prodromal phase of the disease, when they should be regarded as an ongoing progression of the autoimmune disorder.
A newly developed cannabidiol capsule can be absorbed by the body faster and penetrate the brain more quickly in mouse models of neurological disorders such as Alzheimer's disease, multiple sclerosis and TBI.
TET1, a newly identified molecule appears to play a key role in myelin repair. The findings could have implications for the treatment of a range of neurodegenerative diseases, including multiple sclerosis.
Lower serum levels of the sugar metabolite GlcNAc was associated with progressive disability and neurodegeneration in patients with multiple sclerosis.
A 3D mini brain, created from human skin cells, will be used to study myelin.
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··6 min readCombining artificial intelligence technology with brain scan data, researchers have identified three novel subtypes of multiple sclerosis.
Researchers shed new light on how remylination fails in multiple sclerosis. The study reports a drug, currently being studied as a cancer therapy, can alter the key signaling cascades that result in demylination associated with MS.
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··4 min readCombing gait data from multiple sclerosis patients with machine learning, researchers have developed a new tool to monitor and predict disease progression.
When injected with the new mRNA vaccine, mice with multiple sclerosis-like symptoms developed less severe symptoms than would normally occur.
