Treating inflammation with inflammation
Ter119, an inflammatory antibody, has the potential to treat inflammation caused by autoimmune diseases, according to the findings of a new rodent study.... Read More...
Multiple Sclerosis
X chromosome gene may explain why women are more prone to autoimmune diseases
Kdm6a, a gene on the X chromosome appears to be associated with the development of autoimmune diseases, such as Multiple Sclerosis. The gene is expressed more in the immune cells of females than males. When Kdm6a was deleted in mouse models of MS, the animals had improved symptoms and reduced inflammation. The findings shed light on why women are more prone to autoimmune diseases than males.... Read More...
Vegetable-rich Wahls diet lowers fatigue in multiple sclerosis patients by raising good cholesterol
Eating a diet high in vegetables can help reduce symptoms of fatigue in those with progressive multiple sclerosis. ... Read More...
Scientists reverse aging process in rat brain stem cells
Removing Piezo1 from the surface of aged brain stem cells caused the cells to become rejuvenated and regain their normal regenerative function.... Read More...
Smoldering spots in the brain may signal severe MS
Dark rimmed spots on the brain that represent ongoing inflammation, known as chronic active lesions, may be a hallmark of a more aggressive and debilitating form of multiple sclerosis. The findings provide a new biomarker for diagnosing the neurological disorder.... Read More...
Adding MS drug to targeted cancer therapy may improve glioblastoma outcomes
Teriflunomide, a drug commonly used to treat multiple sclerosis, shows promise for the treatment of glioblastoma when coupled with targeted cancer therapies.... Read More...
Vaccinations not a risk factor for multiple sclerosis
A study of over 200,000 people found no evidence that vaccinations increase the risk of developing multiple sclerosis, or the onset of an initial MS episode. ... Read More...
Fingerprint of Multiple Sclerosis Immune Cells Identified
T helper cells in the blood of patients with multiple sclerosis infiltrate the central nervous system, causing inflammation and neural damage. ... Read More...
Study pinpoints cell types affected in brains of multiple sclerosis patients
Projection neurons have been implicated in the progression of multiple sclerosis. A new study reports projection neurons are damaged by immune cells. This damage could contribute to both atrophy and cognitive changes associated with the disease.... Read More...
Gut microbes protect against neurologic damage from viral infections
A healthy and diverse microbiome is essential for quickly clearing viral infections in the nervous system to prevent risks associated with multiple sclerosis. Mice with lower gut bacteria had weaker immune responses and were unable to eliminate viruses, leading to worsening paralysis. Those treated with antibiotics before infection had fewer microglia. ... Read More...
Differences in MS patients’ cerebrospinal fluid may be key to drugs that halt progression
Ceramide exposure impairs the ability for neurons to make energy by directly damaging mitochondria. Additionally, ceramides force neurons to rapidly uptake glucose in order to provide cellular energy. ... Read More...
Are the ‘viral’ agents of MS, ALS and schizophrenia buried in our genome?
Retroviruses may be a missing causal link in diseases like ALS, multiple sclerosis and schizophrenia.... Read More...