Cholesterol synthesis in nerve cells ensures the replenishment of newly myelin-forming cells. The findings could provide new treatment options for the treatment of disorders associated with myelin loss, such as multiple sclerosis.
Analyzing the gene activity of 66,000 cells from human brain tissue, researchers generated a comprehensive map of cell types associated with brain lesions in multiple sclerosis, and their gene expression patterns and interactions.
A new study links viral infections including mononucleosis and pneumonia experienced during adolescence with an increased risk of developing multiple sclerosis.
Piezo1 limits the potential of regulatory T cells (Treg) to mitigate autoimmune neuroinflammation. Inhibiting Piezo1 could lead to new treatments for autoimmune disorders like multiple sclerosis.
Scars and lesions on the brain and spinal cord offer clues as to why progressive disability occurs in patients with multiple sclerosis.
A diet rich in foods containing isoflavone, a plant-based compound found in legumes, chickpeas, and peanuts, that resembles estrogen, protects against multiple sclerosis symptoms in mouse models.
More frequent hospital and doctor's office visits in the years leading up to multiple sclerosis diagnosis with early MS type symptoms are usually associated with a prodromal phase of the disease, when they should be regarded as an ongoing progression of the autoimmune disorder.
A newly developed cannabidiol capsule can be absorbed by the body faster and penetrate the brain more quickly in mouse models of neurological disorders such as Alzheimer's disease, multiple sclerosis and TBI.
TET1, a newly identified molecule appears to play a key role in myelin repair. The findings could have implications for the treatment of a range of neurodegenerative diseases, including multiple sclerosis.
Lower serum levels of the sugar metabolite GlcNAc was associated with progressive disability and neurodegeneration in patients with multiple sclerosis.