Combining Disulfiram, a medication commonly used to treat chronic alcoholism, with copper ions kills medulloblastoma cancer cells and prevents new ones from growing.
A small molecular compound has been discovered that can activate the Wnt pathway in non-Wnt subtypes of medulloblastoma brain cancer, making tumors more responsive to therapies.
The ELP1 gene is abnormally mutated in the germline DNA of 15% of children with the Sonic Hedgehog subgroup of medulloblastoma brain cancer.
Astrocytes hijack microglia for the benefit of tumor growth in medulloblastoma, causing the microglia to produce IGF1. The findings could aid in the development of new treatments for a range of cancers.
Using computer assisted technology to map cell types and molecular cascades, researchers have discovered potential new treatment strategies for recurrent Sonic Hedgehog Medulloblastoma.
Researchers report a targeted therapy that blocks LSD1 effectively shrinks tumor size in mouse models of medulloblastoma, a form of pediatric brain cancer.
A small molecule, 6-thio-dG, may provide a new approach to treating currently untreatable pediatric brain cancers, researchers report.
A new study reports on the benefits of precision medicine for treating pediatric brain cancer.
Brain tumor paint helps improve surgical outcome for brain cancer patient.
Researchers report improved survival rates in people who received chemotherapy postoperatively for medulloblastoma brain cancer.
Three subgroups of medulloblastoma brain cancer can be identified non-invasively using MRS neuroimaging technology.
Researchers find possible markers for brain cancers in the neural crest.
