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Lupus

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·May 14, 2019·4 min read

How stressed-out gut bacteria may trigger autoimmune response

Chronic social stress in mice induces the expression of virulent genes in the gut microbiota. The altered microbiota increases the presence of effector T helper cells in the lymph nodes and induces myelin autoreactive cells. Exposure to chronic stress, therefore, may increase the risk of developing autoimmune diseases for some individuals with a susceptibility.

This shows VGLL3 expression in different skin samples

Featured Neurology Neuroscience Open Neuroscience Articles

·April 19, 2019·5 min read

Skin discovery may help explain why women get autoimmune diseases far more often than men

Skin cells may hold the key to explaining why women are more prone to developing autoimmune diseases, such as lupus than men. Researchers found women have more VGLL3 in their skin cells than men. VGLL3 pushes the immune system into overdrive, resulting in the 'self-attacking' autoimmune response, the mouse study revealed. Findings strongly implicate VGLL3 as a pivotal catalyst in sex-based autoimmunity.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·April 5, 2019·6 min read

Unlocking the female bias in lupus

Disruptions in maintaining X chromosome inactivation of T cells may explain why women are more prone to developing SLE than males.

Featured Neurology Neuroscience

·March 19, 2019·5 min read

Experimental blood test accurately spots fibromyalgia

A new biomarker for fibromyalgia has been identified in blood samples taken from patients suffering from the condition.

Brain Cancer Featured Genetics Neurology Neuroscience

·January 11, 2019·6 min read

A Patient’s Sex Matters When it Comes to Brain Cancer

Researchers report our gender can determine longevity and response to treatment for glioblastoma brain cancer. The study reports male survival is determined by genes that control cell division, where as female survival is often determine by genes that regulate the ability of cancer cells to migrate to different brain areas.

Featured Genetics Neurology

·December 18, 2018·3 min read

A Single Faulty Gene Can Lead to Lupus

Researchers report defects in the Ets1 gene is linked to characteristics associated with systemic lupus erythematosus immune abnormalities.

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·May 28, 2018·4 min read

No Link Between HPV Vaccine and Autoimmune Disorder Risk

Researchers report they have found no increased risk of autoimmune diseases in girls who received the HPV4 vaccine. The study adds to a growing body of evidence for the safety of the vaccine.

Featured Genetics Neurology

·February 28, 2018·4 min read

The Factors that Most Affect Our Immune System

Researchers investigate the different factors that affect our immune system and why some of us are more prone to diseases than others.

Featured Genetics Neurology

·December 5, 2017·5 min read

Investigating Protein’s Role in Lupus Development

A new study reports the loss of the Bim protein in macrophages leads to lupus-like symptoms in mice. The findings may help in the development of new treatments for the autoimmune disease in humans.

Featured Neurology

·October 2, 2017·5 min read

Preventing Autoimmune Disease After Viral Infections

A study in Nature Immunology reports on the mechanism that helps to prevent autoimmune diseases from developing following infection. Researchers report a population of immune cells develop during late stages of the immune response to influenza infection.

Featured Neurology Open Neuroscience Articles

·October 2, 2017·5 min read

Healthy Bacteria in Yogurt May Reduce Lupus Symptoms: Mouse Study

A new study from Virginia Tech reveals a healthy bacteria found in yogurt could reduce some lupus symptoms. The study expands on earlier work from the researchers, noting a lack of Lactobacillus in both mice and humans with lupus.