Researchers report our gender can determine longevity and response to treatment for glioblastoma brain cancer. The study reports male survival is determined by genes that control cell division, where as female survival is often determine by genes that regulate the ability of cancer cells to migrate to different brain areas.
A key finding in the origins of lupus has been discovered. In those with systemic lupus erythematosus, B cells are abnormally activated. This results in the production of antibodies which react against the patient's own tissue, causing a range of symptoms including rashes, joint pain, and fatigue.
A new biomarker for fibromyalgia has been identified in blood samples taken from patients suffering from the condition.
6-gingerol, the main bioactive compound of ginger root, appears to counteract mechanisms that fuel autoimmune disorders such as lupus and antiphospholipid syndrome in mice.
Rare gene variants BLK and BANK1 are present in a substantial percentage of people with Lupus. The genetic variants suppress 1RF5 and type-1 1Fn in B cells, causing dysfunction in the immune cells.
A new study from Virginia Tech reveals a healthy bacteria found in yogurt could reduce some lupus symptoms. The study expands on earlier work from the researchers, noting a lack of Lactobacillus in both mice and humans with lupus.
Chronic social stress in mice induces the expression of virulent genes in the gut microbiota. The altered microbiota increases the presence of effector T helper cells in the lymph nodes and induces myelin autoreactive cells. Exposure to chronic stress, therefore, may increase the risk of developing autoimmune diseases for some individuals with a susceptibility.