Lupus Research Articles - Neuroscience News

This diagram shows how lupus affects the body

B cells off the rails early in lupus

Neuroscience NewsJuly 2, 2019

A key finding in the origins of lupus has been discovered. In those with systemic lupus erythematosus, B cells are abnormally activated. This results in the production of antibodies which react against the patient's own tissue, causing a range of symptoms including rashes, joint pain, and fatigue. ... Read More...

FeaturedGeneticsNeuroscience4 min read

This shows bacteria and a pregnant woman

Women caught in a pickle by their own immune systems

Neuroscience NewsJune 12, 2019

Pregnancy Compensation Hypothesis may explain why women are more prone to developing autoimmune diseases, like multiple sclerosis and lupus, than men.... Read More...

FeaturedNeurologyNeuroscience6 min read

This shows the structure of the compound

New compounds could be used to treat autoimmune disorders

Neuroscience NewsMay 29, 2019

Researchers have developed small molecules that inhibit one of the main enzymes implicated in autoimmune response. The research could lead to potential new medications for a range of autoimmune diseases.... Read More...

FeaturedNeurologyNeuroscienceOpen Neuroscience Articles5 min read

This shows a woman covering her face with her hands

Autoimmune disease and stress: Is there a link?

Neuroscience NewsMay 26, 2019

Researchers consider why those with autoimmune diseases are more likely to have a previous diagnosis of stress-related disorders. ... Read More...

FeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience ArticlesPsychology8 min read

Groundbreaking genetic discovery shows why Lupus develops

Neuroscience NewsMay 17, 2019

Rare gene variants BLK and BANK1 are present in a substantial percentage of people with Lupus. The genetic variants suppress 1RF5 and type-1 1Fn in B cells, causing dysfunction in the immune cells.... Read More...

FeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles5 min read

How stressed-out gut bacteria may trigger autoimmune response

Neuroscience NewsMay 14, 2019

Chronic social stress in mice induces the expression of virulent genes in the gut microbiota. The altered microbiota increases the presence of effector T helper cells in the lymph nodes and induces myelin autoreactive cells. Exposure to chronic stress, therefore, may increase the risk of developing autoimmune diseases for some individuals with a susceptibility.... Read More...

FeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience ArticlesPsychology5 min read

This shows VGLL3 expression in different skin samples

Skin discovery may help explain why women get autoimmune diseases far more often than men

Neuroscience NewsApril 19, 2019

Skin cells may hold the key to explaining why women are more prone to developing autoimmune diseases, such as lupus than men. Researchers found women have more VGLL3 in their skin cells than men. VGLL3 pushes the immune system into overdrive, resulting in the 'self-attacking' autoimmune response, the mouse study revealed. Findings strongly implicate VGLL3 as a pivotal catalyst in sex-based autoimmunity.... Read More...

FeaturedNeurologyNeuroscienceOpen Neuroscience Articles6 min read

Unlocking the female bias in lupus

Neuroscience NewsApril 5, 2019

Disruptions in maintaining X chromosome inactivation of T cells may explain why women are more prone to developing SLE than males.... Read More...

FeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles7 min read

Experimental blood test accurately spots fibromyalgia

Neuroscience NewsMarch 19, 2019

A new biomarker for fibromyalgia has been identified in blood samples taken from patients suffering from the condition. ... Read More...

FeaturedNeurologyNeuroscience7 min read

A Patient’s Sex Matters When it Comes to Brain Cancer

Neuroscience NewsJanuary 11, 2019

Researchers report our gender can determine longevity and response to treatment for glioblastoma brain cancer. The study reports male survival is determined by genes that control cell division, where as female survival is often determine by genes that regulate the ability of cancer cells to migrate to different brain areas.... Read More...

Brain CancerFeaturedGeneticsNeurologyNeuroscience8 min read

A Single Faulty Gene Can Lead to Lupus

Neuroscience NewsDecember 18, 2018

Researchers report defects in the Ets1 gene is linked to characteristics associated with systemic lupus erythematosus immune abnormalities.... Read More...

FeaturedGeneticsNeurology4 min read

No Link Between HPV Vaccine and Autoimmune Disorder Risk

Neuroscience NewsMay 28, 2018

Researchers report they have found no increased risk of autoimmune diseases in girls who received the HPV4 vaccine. The study adds to a growing body of evidence for the safety of the vaccine.... Read More...

FeaturedNeurologyOpen Neuroscience Articles5 min read

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Lupus

B cells off the rails early in lupus

Women caught in a pickle by their own immune systems

New compounds could be used to treat autoimmune disorders

Groundbreaking genetic discovery shows why Lupus develops

Skin discovery may help explain why women get autoimmune diseases far more often than men

Unlocking the female bias in lupus

Experimental blood test accurately spots fibromyalgia

A Patient’s Sex Matters When it Comes to Brain Cancer

A Single Faulty Gene Can Lead to Lupus

No Link Between HPV Vaccine and Autoimmune Disorder Risk