Lupus

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Lupus

Featured Genetics Neuroscience Psychology

·May 11, 2020·9 min read

Researchers pinpoint genes behind sex biases in autoimmune disorders and schizophrenia

A new study reveals why women are more likely to develop autoimmune conditions like lupus and Sjögren's syndrome, and men are more likely to develop schizophrenia. Researchers implicated the C4 gene in sex-based risk factors for autoimmune and psychiatric disorders. Read More

Featured Neurology Neuroscience Open Neuroscience Articles

·August 7, 2019·4 min read

Blood clotting proteins in urine discovered as biomarkers of lupus nephritis

Clotting proteins are elevated in the urine of patients with lupus nephritis. The findings provide a new biomarker for the autoimmune disease. Read More

This diagram shows how lupus affects the body

Featured Genetics Neuroscience

·July 2, 2019·3 min read

B cells off the rails early in lupus

A key finding in the origins of lupus has been discovered. In those with systemic lupus erythematosus, B cells are abnormally activated. This results in the production of antibodies which react against the patient's own tissue, causing a range of symptoms including rashes, joint pain, and fatigue. Read More

This shows bacteria and a pregnant woman

Featured Neurology Neuroscience

·June 12, 2019·4 min read

Women caught in a pickle by their own immune systems

Pregnancy Compensation Hypothesis may explain why women are more prone to developing autoimmune diseases, like multiple sclerosis and lupus, than men. Read More

This shows the structure of the compound

Featured Neurology Neuroscience Open Neuroscience Articles

·May 29, 2019·4 min read

New compounds could be used to treat autoimmune disorders

Researchers have developed small molecules that inhibit one of the main enzymes implicated in autoimmune response. The research could lead to potential new medications for a range of autoimmune diseases. Read More

This shows a woman covering her face with her hands

Featured Genetics Neurology Neuroscience Open Neuroscience Articles Psychology

·May 26, 2019·6 min read

Autoimmune disease and stress: Is there a link?

Researchers consider why those with autoimmune diseases are more likely to have a previous diagnosis of stress-related disorders. Read More

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·May 17, 2019·3 min read

Groundbreaking genetic discovery shows why Lupus develops

Rare gene variants BLK and BANK1 are present in a substantial percentage of people with Lupus. The genetic variants suppress 1RF5 and type-1 1Fn in B cells, causing dysfunction in the immune cells. Read More

Featured Genetics Neurology Neuroscience Open Neuroscience Articles Psychology

·May 14, 2019·4 min read

How stressed-out gut bacteria may trigger autoimmune response

Chronic social stress in mice induces the expression of virulent genes in the gut microbiota. The altered microbiota increases the presence of effector T helper cells in the lymph nodes and induces myelin autoreactive cells. Exposure to chronic stress, therefore, may increase the risk of developing autoimmune diseases for some individuals with a susceptibility. Read More

This shows VGLL3 expression in different skin samples

Featured Neurology Neuroscience Open Neuroscience Articles

·April 19, 2019·5 min read

Skin discovery may help explain why women get autoimmune diseases far more often than men

Skin cells may hold the key to explaining why women are more prone to developing autoimmune diseases, such as lupus than men. Researchers found women have more VGLL3 in their skin cells than men. VGLL3 pushes the immune system into overdrive, resulting in the 'self-attacking' autoimmune response, the mouse study revealed. Findings strongly implicate VGLL3 as a pivotal catalyst in sex-based autoimmunity. Read More

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·April 5, 2019·6 min read

Unlocking the female bias in lupus

Disruptions in maintaining X chromosome inactivation of T cells may explain why women are more prone to developing SLE than males. Read More

Featured Neurology Neuroscience

·March 19, 2019·5 min read

Experimental blood test accurately spots fibromyalgia

A new biomarker for fibromyalgia has been identified in blood samples taken from patients suffering from the condition. Read More

Brain Cancer Featured Genetics Neurology Neuroscience

·January 11, 2019·6 min read

A Patient’s Sex Matters When it Comes to Brain Cancer

Researchers report our gender can determine longevity and response to treatment for glioblastoma brain cancer. The study reports male survival is determined by genes that control cell division, where as female survival is often determine by genes that regulate the ability of cancer cells to migrate to different brain areas. Read More

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