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Kobe University

·June 11, 2025·5 min read

Hidden Protein Defects Behind Autism Identified

Researchers have created a standardized mouse stem cell library containing 63 genetic variants strongly linked to autism spectrum disorder. Using CRISPR gene editing, the team generated mice and diverse tissues from these modified cells, allowing them to model autism at both the cellular and organismal level.

Featured Neuroscience Psychology

·March 29, 2024·6 min read

Age Influences Perception of Self-Presentation

Age significantly impacts how self-presentation, or manipulating others' evaluations of oneself, is perceived, particularly in the context of the protagonist's usual performance. Their study, involving elementary school children and adults, revealed that perceptions of honesty, modesty, and character are nuanced by the protagonist's typical behavior, suggesting that false statements are viewed more negatively as children grow older.

This shows a brain and computer monitor.

Featured Neuroscience

·March 21, 2024·5 min read

AI Predicts Movement from Brain Data

Researchers developed an AI algorithm capable of predicting mouse movement with a 95% accuracy by analyzing whole-cortex functional imaging data, potentially revolutionizing brain-machine interface technology. The team's end-to-end deep learning method requires no data preprocessing and can make accurate predictions based on just 0.17 seconds of imaging data.

Featured Genetics Neuroscience

·March 8, 2024·5 min read

Unlocking Synaptic Mysteries: The Role of FAM81A Protein

Researchers have identified a critical protein, FAM81A, that plays a pivotal role in forming postsynaptic protein agglomerations, essential for synaptic function in the brain. By analyzing 35 previous studies, the team discovered FAM81A's consistent presence in the postsynaptic density, a complex protein structure vital for neuron signal transmission.

Autism Featured Neuroscience

·August 24, 2023·4 min read

Revolutionizing Autism Research in Virtual Reality

Autism, an inherently unique and multi-faceted condition, lacks a standardized diagnostic approach, making treatment and research challenges. A new study highlights the potential of mouse models in autism research, offering insights into molecular and physiological mechanisms.

Autism Featured

·March 28, 2023·7 min read

Using Virtual Reality to Investigate Autism’s Neural Network Dynamics

Combining novel virtual reality imaging with machine learning, researchers were able to accurately detect mouse models of ASD compared to wild-type mice based on cortical functional network dynamics while the animal was in motion.

Autism Featured Genetics Neuroscience

·March 10, 2023·5 min read

Could an Ancient Virus Be a Genetic Driver of Autism?

Genome and transcriptome analysis revealed BTBR autism mouse models have increased levels of endogenous retrovirus genes. BTBR/R models of ASD showed differences in the expression of a variety of genes that are indicative of endogenous retrovirus activation. BTBR/R mice exhibit autistic-like behaviors without reduced learning abilities.

Featured Neurology Neuroscience Open Neuroscience Articles

·May 26, 2022·5 min read

A Biomarker That Can Diagnose Parkinson’s Disease

Researchers have developed a new biomarker that will enable a rapid and inexpensive test for Parkinson's disease.

Autism Featured Genetics Neuroscience Open Neuroscience Articles

·May 2, 2022·4 min read

Does Autism Begin in the Womb?

Researchers found idiopathic autism occurs as the result of epigenetic abnormalities in hematopoietic cells during fetal development, leading to immune dysregulation in the brain and gut.

Autism Featured Genetics Neuroscience Open Neuroscience Articles

·July 9, 2021·6 min read

New Genetic Driver of Autism and Other Developmental Disorders Identified

A new mouse study identifies the Necdin (Ndn) gene as a causal factor of autism with 15q11-q13 chromosomal abnormality.

Featured Neuroscience

·June 18, 2021·6 min read

How Childhood Exercise Could Maintain and Promote Cognitive Function in Later Life

Children who are physically active have higher cognitive function and increased functional connectivity in the brain later in life than those who are less active, a new study reports.