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Karolinska Institute

Featured Genetics Neuroscience Open Neuroscience Articles

·August 23, 2020·3 min read

Study Reveals the Unfolding of Neuronal Fate

Study combines developmental neurobiology and computational neuroscience to explore the dynamic changes of gene expression at the single-cell level as progenitor cells differentiate into neurons, then diversify into different sensory neurons.

Featured Neuroscience Open Neuroscience Articles Psychology

·June 1, 2020·4 min read

How ketamine combats depression

Ketamine increases the number of serotonin 1B receptors. Ketamine binds to serotonin 1B receptors, reducing the release of serotonin and increasing the release of dopamine.

This shows the shadow of a man in a tunnel

Featured Neuroscience Open Neuroscience Articles Psychology

·April 29, 2020·5 min read

Drug reduces risk of pedophiles re-offending

Degarelix, a drug that reduces testosterone levels, shows potential in the treatment of pedophilic disorder. Men with a history of child sexual abuse who took the drug had reduced overall sexual desire and decreased attraction toward children, with noticeable effects within two weeks.

Featured Genetics Neurology Neuroscience

·April 27, 2020·3 min read

More evidence Parkinson’s disease may start in the gut

Enteric neurons appear to play a key role in the development of Parkinson's disease. The findings support the hypothesis and previous studies that the neurodegenerative disease may start in the gut before spreading to the brain. Researchers also found oligodendrocytes were affected during the early stages of Parkinson's, even before the loss of dopaminergic neurons.

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·April 2, 2020·4 min read

Trial drug may block early stages of COVID-19, human cell study shows

hrsACE2, a genetically modified protein already being tested to prevent lung disease, reduces the viral growth of SARS-CoV-2 by a factor of 1,000 to 5,000 in human cell cultures. Researchers believe the enzyme copy lures the virus to attach itself to the copy, rather than human lung cells. The findings suggest hrsACE2 could significantly block the early stages of SARS-CoV-2 infections and prevent COVID-19 from becoming severe.

This shows an apartment building next to a smoke stack

Featured Neurology Neuroscience Open Neuroscience Articles

·March 30, 2020·4 min read

Air pollution linked to dementia and cardiovascular disease

Long-term air pollution exposure was associated with a higher risk of dementia. Ischemic heart disease and heart failure appeared to enhance the link between air pollution and dementia.

Featured Neuroscience Open Neuroscience Articles

·March 23, 2020·4 min read

COVID-19 pandemic likely to go in waves

A new mathematical model shows the current COVID-19 pandemic could decline during the summer months, but return in the fall, with a major resurgence next winter. The model takes into account the seasonal variations of other closely related respiratory coronaviruses. Based on other coronavirus data, the model reveals infections were ten times more common between December and April in the northern hemisphere than between July and September. Researchers emphasize this model only attempts to examine possible scenarios, as we are currently unsure how warmer temperatures will affect SARS-CoV-2.

Featured Neuroscience

·March 16, 2020·3 min read

New study reveals early evolution of cortex

Lamprey brain study provides new insights into how the human brain evolved.

Featured Genetics Neuroscience Open Neuroscience Articles

·March 6, 2020·5 min read

One step closer to understanding the human brain

Researchers have launched a comprehensive overview of protein expression in the brain. A newly launched open-access database is available for researchers to use.

Featured Neuroscience Open Neuroscience Articles Psychology

·January 10, 2020·5 min read

Long-term medication for schizophrenia is safe

Long-term antipsychotic use does not increase the risk of physical morbidity leading to hospitalization.

Featured Neuroscience Open Neuroscience Articles

·December 27, 2019·3 min read

A molecular map of the brain’s decision-making area

Using RNA sequencing, researchers have created a spatiomolecular map of the striatum, an area of the brain implicated in decision making and addiction.