Researchers identified a new mechanism by which auditory sensitivity is regulated. The mechanism can temporarily reduce sensitivity in the auditory system to protect itself from loud sounds that can cause hearing damage.
Researchers have revealed the 3d structure of the Flycatcher1 protein channel which enables the Venus flytrap to close in response to prey. The findings shed light on how other mechanosensitive ion channels may operate in other plants, bacteria, and the human body.
Human neurons have fewer ion channels compared to other animals. The reduced number of ion channels may have allowed the human brain to divert energy to other neural processes, researchers say.
When necrotic cells expose phosphatidylserine on their outer surfaces, and when phagocytes detect it, the phagocytes ingest and destroy the dying cells.
Too much salt can disrupt the energy balance of immune cells and prevent them from functioning correctly.
Researchers have discovered a potential new way to reduce levels of hydrogen sulfide in rats' brains. Decreasing H2S levels decreases the damage the toxic gas can cause, and ultimately may pave the way for the development of new treatments for dementia and epilepsy.
The ion channel TRPC5 acts as a molecular cold sensor in teeth. Researchers report the TRPC5 could be a new target to help treat pain from toothaches and cold sensitivity.
Ezogabine, a drug that opens up the KCNQ2/3 type potassium channel, significantly improved symptoms of depression and anhedonia.
Findings suggest cell-to-cell transmission of cGAMP via LRRC8/VRAC ion channels is central to effective antiviral immunity.
Ion channels use a "ball-and-chain" mechanism to help regulate ion flow. Findings confirm a long-standing hypothesis about ion channels and provide key advances in understanding the basic biological processes at work.
Researchers report newborn granule cells in the dentate gyrus become less excitable after three weeks. The loss of excitability is crucial for the functioning of mature neurons.
Researchers report new findings about the immune system could help treat inflammation in Alzheimer's disease and could save people from deadly inflammation associated with sepsis.
