When necrotic cells expose phosphatidylserine on their outer surfaces, and when phagocytes detect it, the phagocytes ingest and destroy the dying cells. Read More
Too much salt can disrupt the energy balance of immune cells and prevent them from functioning correctly. Read More
Researchers have discovered a potential new way to reduce levels of hydrogen sulfide in rats' brains. Decreasing H2S levels decreases the damage the toxic gas can cause, and ultimately may pave the way for the development of new treatments for dementia and epilepsy. Read More
The ion channel TRPC5 acts as a molecular cold sensor in teeth. Researchers report the TRPC5 could be a new target to help treat pain from toothaches and cold sensitivity. Read More
Ezogabine, a drug that opens up the KCNQ2/3 type potassium channel, significantly improved symptoms of depression and anhedonia. Read More
Findings suggest cell-to-cell transmission of cGAMP via LRRC8/VRAC ion channels is central to effective antiviral immunity. Read More
Ion channels use a "ball-and-chain" mechanism to help regulate ion flow. Findings confirm a long-standing hypothesis about ion channels and provide key advances in understanding the basic biological processes at work. Read More
Researchers report newborn granule cells in the dentate gyrus become less excitable after three weeks. The loss of excitability is crucial for the functioning of mature neurons. Read More
Researchers report new findings about the immune system could help treat inflammation in Alzheimer's disease and could save people from deadly inflammation associated with sepsis. Read More
Using cryo-electron microscopy, researchers have been able to capture how glutamate opens glutamate receptor ion channels. The Nature study provides significant insight into how receptors can mediate brain function. Read More
Findings from a study of naked mole rats could be important for helping develop pain therapies for humans. Read More
Researchers have detailed the structure of the Slo2.2 channel and offer new insights into how this channel works. Read More
