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inflammation

·August 15, 2025·4 min read

Gut Neurons Direct Immune Healing After Inflammation

Researchers have discovered that neurons in the gut play a direct role in guiding immune healing after inflammation by producing a molecule called adrenomedullin 2 (ADM2). This molecule stimulates group 2 innate lymphoid cells (ILC2s) to release amphiregulin, a tissue-repairing factor, offering protection in models of inflammatory bowel disease.

Featured Neuroscience Psychology

·July 23, 2025·7 min read

Inflammation Influences Cannabis’s Effects on Anxiety and Sleep

A new study shows that inflammation levels influence how cannabis affects anxiety and sleep quality. Researchers found no overall change in inflammatory markers after 4 weeks of cannabis use, but baseline inflammation moderated outcomes.

This shows a woman holding her head in pain.

Featured Neuroscience Pain

·July 20, 2025·5 min read

How Stress Sounds Amplify Pain and Inflammation

Pain isn’t just physical—it can be socially and emotionally transmitted. New research shows that ultrasonic vocalizations emitted by mice in pain trigger hyperalgesia in nearby mice, even without direct injury.

Featured Genetics Neurology Neuroscience

·July 12, 2025·5 min read

Gene Key to MS Immune Regulation Discovered

New research has identified the gene Egr-1 as a critical regulator of immune balance, offering hope for autoimmune disease therapies. In a mouse model of multiple sclerosis, loss of Egr-1 led to reduced regulatory T cell activity and heightened inflammation. T

Featured Neuroscience

·July 2, 2025·5 min read

Aging May Not Equal Chronic Inflammation

A new global study challenges the long-held belief that chronic inflammation is a universal marker of aging. Researchers compared industrialized populations with Indigenous groups and found that "inflammaging" is strongly tied to lifestyle and environmental exposures.

This shows an older person walking in a street and a brain.

Featured Neurology Neuroscience

·June 26, 2025·3 min read

Neighborhood Disadvantage Linked to Alzheimer’s Biomarkers and Inflammation

Living in disadvantaged neighborhoods may increase the risk of Alzheimer’s disease by elevating biomarkers associated with inflammation and neurodegeneration. A long-term study of 334 older adults found higher levels of tau and YKL-40, biomarkers linked to Alzheimer’s and brain inflammation, in people from less advantaged areas.

Featured Neuroscience Psychology

·June 25, 2025·4 min read

Autoimmune Disease Doubles Risk of Depression and Anxiety

People living with autoimmune diseases face nearly twice the risk of developing persistent mental health disorders like depression, anxiety, and bipolar disorder, according to a massive UK-based study. Researchers suggest chronic inflammation may play a key role in this connection, especially in women who showed significantly higher risk levels than men.

Featured Neurology Neuroscience

·June 24, 2025·3 min read

PET Imaging Maps Brain Inflammation in Progressive Speech Disorder

A novel PET imaging study has identified unique patterns of neuroinflammation in patients with progressive apraxia of speech (PAOS), a rare disorder that impairs the brain’s ability to plan speech. Using TSPO PET scans, researchers found elevated inflammation in brain regions involved in movement and speech, particularly in patients who also showed signs of Parkinson-plus syndromes.

Featured Genetics Neurology Neuroscience

·June 24, 2025·5 min read

Rare Mutation Shields Brain from Alzheimer’s by Silencing Inflammation

A rare genetic mutation known as APOE3-R136S, or the “Christchurch mutation,” appears to protect against Alzheimer’s disease by suppressing inflammatory signaling in the brain’s immune cells. Researchers found that this mutation dampens the cGAS-STING pathway, a key innate immune mechanism that is abnormally activated in Alzheimer’s and other neurodegenerative disorders.

This shows the outline of a child and a brain.

Featured Neuroscience Psychology

·June 12, 2025·6 min read

Childhood Trauma Rewires the Brain Through Inflammation

Childhood trauma doesn't just leave psychological scars—it biologically reshapes the brain through chronic neuroinflammation and structural changes, increasing vulnerability to psychiatric disorders later in life. New research shows that early adversity can reprogram immune responses, altering lifelong mental health outcomes.

Featured Genetics Neurology Neuroscience

·June 2, 2025·6 min read

Blocking Brain Inflammation Molecule May Halt Alzheimer’s

A new study has uncovered a surprising culprit in the progression of Alzheimer’s disease: the immune molecule STING. Scientists found that STING, normally involved in defending the brain, becomes hyperactive with age, causing harmful inflammation and accelerating brain damage.

Featured Neuroscience

·June 1, 2025·7 min read

T Cells Found Living in Healthy Brains

Contrary to long-standing beliefs, T cells—key immune cells—have been discovered in the healthy brains of both mice and humans. These cells, previously thought to only enter the brain during disease, were most concentrated in a region that regulates hunger and thirst.