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inflammation

·November 25, 2025·7 min read

Your Brain Has a Built-In Isolation Mode

New research uncovers the exact immune-to-brain pathway that drives the loss of social motivation during sickness. Scientists showed that when the cytokine IL-1β binds to receptors on neurons within the dorsal raphe nucleus, it activates a circuit that reduces social interaction.

Featured Genetics Neurology Neuroscience

·November 5, 2025·6 min read

3D Brain Map Reveals How Inflammation Reawakens Developmental Genes

Researchers have developed the most detailed molecular map yet of how the brain develops and reacts to inflammation, revealing that disease processes can “reawaken” genes from early life. Using a new spatial tri-omics technique, the team tracked how gene activity, epigenetic changes, and protein production interact in specific brain regions.

Featured Neurology Neuroscience

·October 10, 2025·7 min read

Inflammatory Brain Cells Driving Progressive MS Discovered

Researchers have identified a rare type of brain cell that may drive the chronic inflammation and neurodegeneration seen in progressive multiple sclerosis (MS). These cells, called disease-associated radial glia-like (DARG) cells, appear six times more often in patients with progressive MS than in healthy individuals.

Featured Neurology Neuroscience

·October 8, 2025·9 min read

Human Brain-on-a-Chip Reveals How Inflammation Breaks the Mind

Researchers have developed brain-on-a-chip technology that uses human tissue to model how the brain’s protective barrier breaks down during inflammation and disease. The system replicates the blood-brain barrier, showing how cytokine storms and leaked blood proteins can trigger harmful changes in brain cells.

Featured Neurology Neuroscience

·October 6, 2025·4 min read

CBD Calms the Inflamed Alzheimer’s Brain

A new study reveals that cannabidiol (CBD) can significantly reduce neuroinflammation associated with Alzheimer’s disease. In experiments using an Alzheimer’s mouse model, researchers found that inhaled CBD lowered the activity of key genes driving inflammation and decreased harmful proinflammatory molecules in the brain.

This shows a pregnant woman surrounded by viruses.

Featured Neuroscience

·September 24, 2025·6 min read

Severe Flu in Pregnancy Lets Harmful Molecules Reach Fetal Brain

A new study shows that severe flu infections in pregnant mice compromise both placental and brain barriers, allowing large molecules and fibrinogen to reach the fetal brain. These molecules accumulated in critical regions like the subventricular zone, where neural stem cells develop, raising concerns about long-term impacts on neurodevelopment.

Featured Neuroscience

·September 20, 2025·6 min read

Cocoa Flavanols Show Anti-Inflammatory Effects

A large clinical trial found that cocoa flavanol supplements can lower age-related inflammation, potentially explaining their heart-protective effects. Researchers analyzed blood samples and discovered a consistent reduction in hsCRP, a biomarker tied to cardiovascular risk, among participants taking cocoa extract.

Featured Neuroscience

·August 15, 2025·4 min read

Gut Neurons Direct Immune Healing After Inflammation

Researchers have discovered that neurons in the gut play a direct role in guiding immune healing after inflammation by producing a molecule called adrenomedullin 2 (ADM2). This molecule stimulates group 2 innate lymphoid cells (ILC2s) to release amphiregulin, a tissue-repairing factor, offering protection in models of inflammatory bowel disease.

Featured Neuroscience Psychology

·July 23, 2025·7 min read

Inflammation Influences Cannabis’s Effects on Anxiety and Sleep

A new study shows that inflammation levels influence how cannabis affects anxiety and sleep quality. Researchers found no overall change in inflammatory markers after 4 weeks of cannabis use, but baseline inflammation moderated outcomes.

This shows a woman holding her head in pain.

Featured Neuroscience Pain

·July 20, 2025·5 min read

How Stress Sounds Amplify Pain and Inflammation

Pain isn’t just physical—it can be socially and emotionally transmitted. New research shows that ultrasonic vocalizations emitted by mice in pain trigger hyperalgesia in nearby mice, even without direct injury.

Featured Genetics Neurology Neuroscience

·July 12, 2025·5 min read

Gene Key to MS Immune Regulation Discovered

New research has identified the gene Egr-1 as a critical regulator of immune balance, offering hope for autoimmune disease therapies. In a mouse model of multiple sclerosis, loss of Egr-1 led to reduced regulatory T cell activity and heightened inflammation. T

Featured Neuroscience

·July 2, 2025·5 min read

Aging May Not Equal Chronic Inflammation

A new global study challenges the long-held belief that chronic inflammation is a universal marker of aging. Researchers compared industrialized populations with Indigenous groups and found that "inflammaging" is strongly tied to lifestyle and environmental exposures.