A two-week course of CBD helps normalize and restore the function of two proteins associated with reducing amyloid-beta accumulation in mouse models of familial Alzheimer's disease. CBD also reduces levels of IL-6, an immune protein associated with inflammation in Alzheimer's patients.
From impairing nervous system function and changing bacterial communities in the microbiome to increasing oxidative stress and inflammation, researchers report on the ways in which exposure to chemical pollution harms the body.
The protein Arginase-2 works through mitochondria to reduce inflammation. The findings could lead to new treatments for diseases associated with neuroinflammation, including multiple sclerosis and rheumatoid arthritis.
MRC1+ macrophages are dysfunctional in animal models of neuropathic pain. Stimulating the expression of the anti-inflammatory protein CD163 reduced signs of neuroinflammation in the spinal cords of mice with neuropathic pain.
Astrocytes derived from pluripotent stem cells of bipolar patients provide suboptimal support for neural activity. The malfunction can be traced to the inflammation-promoting molecule, interleukin-6.
A new drug modulates, rather than inhibits, a key enzyme implicated in the formation of Alzheimer's related plaques.
Taking omega-3 supplements may help to reduce muscle soreness following exercise. Researchers found omega-3 reduced inflammation and decreased muscle damage post exercise.
Study finds the immune system links personality to the long-term risk of mortality. Those who score higher on the personality trait of conscientiousness tend to live longer because their immune systems have lower levels of interleukin-6.
Chronic increases of the cytokine IL-17a circulating in the blood of mice reduced microglia activity in one region of the hippocampus, an area of the brain critical for memory and learning.
People with the APOE4 genetic risk factor for Alzheimer's disease also have lower levels of the CRP inflammatory molecules in their spinal fluid. Researchers speculate these inflammatory molecules may be accumulating in the brain and causing damage, rather than floating freely in cerebrospinal fluid.
Many patients report symptoms of "brain fog" and confusion as a result of COVID-19 infection. Researchers report inflammatory molecules in the cerebral spinal fluid could be the cause of brain fog associated with coronavirus. Anti-inflammatory drugs, such as steriods, could help alleviate the symptoms of COVID brain.