NapA, a protein associated with the peptidoglycan of Borrelia burgdorferi, plays an amplifying role in causing inflammation in Lyme disease associated arthritis.
A new case study reveals medical marijuana may provide rapid relief for sufferers of chronic itch. Researchers say THC attaches itself to brain receptors that influence the nervous system. This reduces inflammation and nervous system activity, leading to a reduction in itch sensation.
Study finds evidence of inflammation in the blood of patients during the early stages of Parkinson's disease. The findings support the theory that inflammation is a driver of the neurodegenerative disorder. The effect was most noticed in women with Parkinson's.
Noradrenaline impairs immune response by inhibiting the movement of leukocytes to different tissue.
Researchers have identified acute transverse myelitis (ATM) in a number of COVID-19 patients. ATM, which is marked by inflammation of the spinal cord, is a rare neurological disorder that can lead to spinal cord lesions, paralysis, and bowel dysfunction.
People with schizophrenia and other neuropsychiatric disorders may have a more permissive blood-brain barrier which allows the immune system to become more actively involved in the central nervous system. The resulting inflammation may contribute to the clinical manifestation of psychosis-like symptoms.
COVID-19 may not directly infect the brain, but the virus is still capable of causing significant neurological damage, a new study reports. Researchers say the neurological changes seen as a result of coronavirus infection are likely related to inflammation triggered by viral infection in different parts of the body or the brain's blood vessels.
Researchers link the inflammation associated with chronic sinus infections to alterations in brain activity in networks that govern cognition, external stimuli, and introspection. The findings shed light on why people suffering from sinus infections often report poor concentration and other short-term cognitive problems.
Cysteine leukotriene receptor 2 appears to be a key player in chronic itch, a new study reports.
A new study reveals some experimental antibody treatments for neurodegenerative disorders increase neuroinflammation. The effect was seen in human microglia, not mouse microglia. This may explain why mouse studies have shown these treatments to be effective, but the effect has not been replicated in human studies.
Chronic viral infections have a profound and lasting impact on the immune system in a similar way to aging. Chronic inflammation that occurs as a result of immune system dysregulation is often seen in diseases associated with aging.
Immune cells in the uterus and placenta of stressed pregnant mice were not activated, but researchers found increased levels of inflammation in the developing fetal brain. Additionally, prenatal stress led to reductions in gut microbial strains and functions, especially in those linked to inflammation.
