Study reveals how two key molecules, Rab27b, and epiregulin, interact to contribute to radioresistance in glioblastoma brain cancer. Read More
SARS-CoV-2, the virus responsible for COVID-19, enters human cells by attaching to ACE2 and utilizing TMPRSS2. Drugs that block ACE2 or inhibit the enzyme could help treat the coronavirus, but only during early infection. As the infection progresses, SARS-CoV-2 becomes engulfed in human cells, reducing the number of ACE2 receptors on a cell and leading to an increase of angiotensin II in the blood. Angiotensin II triggers an inflammatory pathway, providing a positive feedback cycle, named IL-6 amplifier, resulting in excessive immune activation and the cytokine storm associated with severe COVID-19. Read More
Inhibitory inputs to the neural circuit between the dorsolateral bed nucleus of the stria terminalis (dlBNST) to the ventral tegmental area (VTA) increase when a person is in chronic pain. This alteration is mediated by enhanced corticotropin-releasing factor signaling within the dlBNST, leading to suppression of the mesolimbic dopaminergic system. The result is depressive mood and anhedonia associated with chronic pain. Read More
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Whether a person is familiar to the animal or not, horses integrate human facial expressions and vocal tones to perceive human emotion, a new study reports. Read More
A positive nod can go a long way to help boost your likability and approachability, researchers report. Read More
According to a PNAS study, the RNAs of tick borne encephalitis virus (TBEV) are transported from the cell body to dendrites. The viral RNAs then reproduce the viruses within the dendrites, disturbing neural activity. Read More
Researchers reveal the role GLAST plays in establishing and maintaining neural wiring of Purkinje cells. Read More
A new study reveals that dancing, not signing, is the primary sexual signal for Java sparrows. Read More
