glioblastoma multiforme

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glioblastoma multiforme

Brain Cancer Featured Genetics Open Neuroscience Articles

·July 14, 2020·4 min read

Gene Responsible for Glioblastoma Identified

An oncogene believed to be responsible for glioblastoma brain cancer has been identified. AVIL, a gene that normally helps cells to maintain their shape and size, can shift into overdrive, causing cancer cells to form and spread. Blocking the gene's activity completely destroyed glioblastoma cancer cells in mouse models, but did not have any effect on healthy cells. The findings provide potential new treatment avenues for the deadly brain cancer. Read More

Brain Cancer Featured Neurology Neuroscience Psychology

·May 1, 2020·3 min read

Schizophrenia drug combined with radiation shows promise in treating deadly brain tumors

Trifluoperazine, a dopamine receptor antagonist commonly prescribed for schizophrenia, used in combination with radiation therapy delays the growth of glioblastoma brain tumors and prolongs survival for brain cancer. Read More

Brain Cancer Featured Neurology Neuroscience

·April 27, 2020·2 min read

CBD shows promise for fighting aggressive brain cancer

Cannabidiol (CBD) appears to slow the growth of glioblastoma brain cancer cells in both animal and human cell lines. CBD's anti-cancer actions target mitochondria, causing them to dysfunction and release harmful reactive oxygen species. Cancer cells treated with CBD exhibited significant decreases in mitochondrial activity. Read More

Brain Cancer Featured Neurology Neuroscience

·April 2, 2020·3 min read

Common vitamin combined with chemotherapy helps immune cells attack glioblastoma

Combining niacin, or vitamin B3, with chemotherapy, helped slow the progression and increase life span in mouse models of glioblastoma. Read More

Brain Cancer Featured Neurology Neuroscience

·January 16, 2020·3 min read

Improved brain chip for precision treatment of brain cancer

A new brain chip allows multiple simultaneous drugs to be administered directly to glioblastoma brain cancer tumors. Read More

This is a drawing of a brain in a castle

Brain Cancer Featured Genetics Neurology Neuroscience

·January 15, 2020·3 min read

Scientists breach brain barriers to attack tumors

Introducing VEGF-C into the cerebrospinal fluid of mouse models of glioblastoma, researchers noted increased levels of T cell response to the cancerous tumors. When combined with immune system checkpoint inhibitors, the VEGF-C treatment significantly extended the life span of the mice with glioblastoma brain cancer. Read More

Brain Cancer Featured Genetics Neurology Neuroscience

·November 21, 2019·5 min read

Non-coding DNA located outside chromosomes may help drive glioblastoma

Extra DNA is critical for maintaining cancer-causing gene activation and supporting the cancer cell's ability to survive. Read More

Brain Cancer Featured Neurology Neuroscience

·September 14, 2019·4 min read

Existing drug could treat aggressive brain cancer

Surfen, a compound molecule used for drug delivery of insulin could block tumor growth for patients with glioblastoma brain cancer. Read More

Brain Cancer Featured Neurology Neuroscience

·August 27, 2019·4 min read

Researchers take aim at circadian clock in deadly brain cancer

Glioblastoma stem cells' circadian clocks ramp up the cells' metabolism, making them stronger, more resistant to treatment, and able to divide and multiply more rapidly. By targeting the stem cells with a small molecule drug, researchers found mice models lived longer and their tumors shrank. Read More

Brain Cancer Featured Neurology Neuroscience Open Neuroscience Articles

·August 19, 2019·4 min read

Glioblastoma brain cancer could be diagnosed with simple blood test in future

Novel biomarkers for glioblastoma brain cancer have been identified in bodily fluids. The discovery may lead to a new, simple, non-invasive blood test to detect brain cancer in the future. Read More

This shows brain slices with a glioblastoma tumor

Brain Cancer Featured Neurology Neuroscience

·August 8, 2019·5 min read

Adding MS drug to targeted cancer therapy may improve glioblastoma outcomes

Teriflunomide, a drug commonly used to treat multiple sclerosis, shows promise for the treatment of glioblastoma when coupled with targeted cancer therapies. Read More

Brain Cancer Featured Genetics Neurology Neuroscience

·July 19, 2019·6 min read

Study hints at why an aggressive form of brain cancer is hard to treat

Genetics and microenvironment influence the frequency of glioblastoma cells. Researchers provide a new blueprint for glioblastoma, integrating the malignant cell programs, cancer cell plasticity, and modulation by genetic drivers. The findings shed light on why this form of cancer is so hard to treat effectively. Read More

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