Improved brain chip for precision treatment of brain cancer
A new brain chip allows multiple simultaneous drugs to be administered directly to glioblastoma brain cancer tumors.... Read More...
glioblastoma multiforme
Scientists breach brain barriers to attack tumors
Introducing VEGF-C into the cerebrospinal fluid of mouse models of glioblastoma, researchers noted increased levels of T cell response to the cancerous tumors. When combined with immune system checkpoint inhibitors, the VEGF-C treatment significantly extended the life span of the mice with glioblastoma brain cancer.... Read More...
Non-coding DNA located outside chromosomes may help drive glioblastoma
Extra DNA is critical for maintaining cancer-causing gene activation and supporting the cancer cell's ability to survive.... Read More...
Existing drug could treat aggressive brain cancer
Surfen, a compound molecule used for drug delivery of insulin could block tumor growth for patients with glioblastoma brain cancer.... Read More...
Researchers take aim at circadian clock in deadly brain cancer
Glioblastoma stem cells' circadian clocks ramp up the cells' metabolism, making them stronger, more resistant to treatment, and able to divide and multiply more rapidly. By targeting the stem cells with a small molecule drug, researchers found mice models lived longer and their tumors shrank.... Read More...
Glioblastoma brain cancer could be diagnosed with simple blood test in future
Novel biomarkers for glioblastoma brain cancer have been identified in bodily fluids. The discovery may lead to a new, simple, non-invasive blood test to detect brain cancer in the future.... Read More...
Adding MS drug to targeted cancer therapy may improve glioblastoma outcomes
Teriflunomide, a drug commonly used to treat multiple sclerosis, shows promise for the treatment of glioblastoma when coupled with targeted cancer therapies.... Read More...
Study hints at why an aggressive form of brain cancer is hard to treat
Genetics and microenvironment influence the frequency of glioblastoma cells. Researchers provide a new blueprint for glioblastoma, integrating the malignant cell programs, cancer cell plasticity, and modulation by genetic drivers. The findings shed light on why this form of cancer is so hard to treat effectively.... Read More...
Scientists track brain tumor turncoats with advanced imaging
Advanced imaging techniques visualize macrophages in brain tumors in mouse models of glioblastoma. ... Read More...
Study finds macrophages’ pathway to nurture PTEN-deficient glioblastoma: Mouse study
PTEN deficiency drives an increased expression of LOX. LOX attracts macrophages which protect gliobastoma brain cancer cells and provide growth factor support for the tumor, a new mouse study reveals.... Read More...
Pairing of glutamine-targeting drug and ketogenic diet fights glioblastoma in mice
Combining an antibiotic drug that targets glutamine with the ketogenic diet helps kill glioblastoma cancer cells, reversing symptoms of the disease and improving survivability in mouse models.... Read More...
New glioblastoma vaccine shows promising results in phase Ib clinical trial
A new vaccine for glioblastoma brain cancer suspends tumor growth and is well tolerated by patients, according to the results of an early phase clinical trial.... Read More...