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Genetics

Featured Genetics Neuroscience Psychology

·November 24, 2025·9 min read

Genetics Point to a New Type of Suicide Risk

New research shows that many people who die by suicide without prior suicidal thoughts or behaviors are not simply “missed cases”—they may have an entirely different underlying risk profile. Genetic analyses of more than 2,700 deaths revealed that these individuals carry fewer genetic risk factors for major psychiatric conditions compared to those with known suicidality.

Featured Genetics Neurology Neuroscience

·November 21, 2025·6 min read

Genetics Plus Heart Health Markers Sharpen Dementia Risk

New research shows that dementia risk is best predicted by combining genetic vulnerability with cardiovascular disease markers, revealing a more precise and actionable way to identify who is most likely to develop the condition. While genes such as APOE4 and family history contribute heavily, equally powerful are modifiable factors like hypertension, obesity, and diabetes.

Featured Genetics Neuroscience Visual Neuroscience

·November 18, 2025·6 min read

Night-Vision Disorders Share a Surprising Cellular Trigger

New research reveals that the loss of a single ion channel, TRPM1, is enough to produce persistent rhythmic oscillations in the retina, a feature observed in both congenital stationary night blindness and retinitis pigmentosa. By comparing Trpm1 and mGluR6 knockout mice, researchers identified a disrupted circuit between rod bipolar cells and AII amacrine cells that produces anti-phase oscillations interfering with visual signaling.

Featured Neuroscience Psychology

·November 18, 2025·7 min read

Rare ADHD Gene Variants Linked to 15-Fold Higher Risk

A massive international genetic study has uncovered rare, high-effect variants in three specific genes—MAP1A, ANO8 and ANK2—that dramatically increase the likelihood of developing ADHD. These variants, though extremely uncommon, strongly affect genes expressed in dopaminergic and GABAergic neurons, influencing brain development from fetal life onward.

Featured Genetics Neuroscience

·November 14, 2025·5 min read

Genetic Roots of Depression Reveal Strong Suicide Risk Signals

New research shows that depression beginning before age 25 has a much stronger hereditary component than depression that emerges later in life. By analyzing genetic data from over 150,000 people with depression, researchers identified distinct genetic regions linked specifically to early-onset cases.

Featured Genetics Neuroscience

·November 12, 2025·5 min read

Genome Study Reveals True Genetic Influence on Traits

Using full genome sequencing data from more than 347,000 individuals, researchers quantified how much genetic differences explain human traits such as height, body mass index, fertility, and disease risk. The results show that genes account for roughly 30% of the variation between individuals, with higher estimates for traits like height and lower for fertility.

Autism Featured Genetics Neuroscience

·November 11, 2025·6 min read

Autism and ADHD Brain Patterns Reveal Shared Biological Roots

A new study shows that autism symptom severity, rather than a formal diagnosis, aligns with shared brain-connectivity patterns across children diagnosed with autism or ADHD. Stronger autistic traits were linked to heightened connectivity between frontoparietal and default-mode networks, regions central to social cognition and executive functions.

Featured Neuroscience

·November 6, 2025·6 min read

New Study Uncovers the Structural Key to How Cells Ship Cargo

Researchers have identified a previously unknown “hook-like” domain in the tail of the kinesin-2 motor protein that explains how these molecular machines select the right cargo inside cells. Using cryo-electron microscopy and simulations, the team mapped the HAC domain’s atomic structure and showed how it binds both adaptor proteins and cargo, forming a highly specific recognition interface.

Featured Genetics Neurology Neuroscience

·November 5, 2025·6 min read

3D Brain Map Reveals How Inflammation Reawakens Developmental Genes

Researchers have developed the most detailed molecular map yet of how the brain develops and reacts to inflammation, revealing that disease processes can “reawaken” genes from early life. Using a new spatial tri-omics technique, the team tracked how gene activity, epigenetic changes, and protein production interact in specific brain regions.

Featured Genetics Neuroscience

·November 4, 2025·7 min read

AI Maps the Brain’s Hidden Bridge, Revealing Genetic Links to Mental Health

For the first time, scientists have mapped the genetic architecture of the brain’s communication bridge—the corpus callosum—using AI and MRI data from over 50,000 people. The study uncovered dozens of genes that shape this vital structure’s size and thickness, many active during prenatal development when the brain’s wiring is established.

Featured Genetics Neurology Neuroscience

·November 4, 2025·6 min read

BrainSTEM Atlas Maps Every Cell of the Developing Human Brain

Scientists have built one of the most comprehensive single-cell maps of the developing human brain. The new BrainSTEM framework analyzed nearly 680,000 fetal brain cells to chart their growth and interactions, offering a detailed reference for studying neuron development.

Featured Genetics Neurology Neuroscience

·November 3, 2025·5 min read

Antioxidant Defense System in the Brain Discovered

A new study identifies biliverdin reductase A (BVRA) as a crucial enzyme defending neurons from oxidative stress, acting independently of its traditional role in bilirubin production. Using genetically modified mice, researchers found that BVRA binds directly to NRF2, a master regulator of antioxidant defense, ensuring the activation of protective genes that maintain cellular health.