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Genetics

Featured Genetics Neurology Neuroscience

·June 5, 2025·7 min read

HIV Drugs Linked to Lower Alzheimer’s Risk

FDA-approved HIV drugs targeting reverse transcriptase (RT) may reduce Alzheimer’s risk by blocking similar enzymatic activity in the aging brain. Scientists discovered unexpected RT activity in neurons of healthy and Alzheimer’s brains, tracing it to truncated LINE1 elements—ancient genetic sequences capable of copying themselves via RT.

Featured Genetics Neuroscience

·June 3, 2025·6 min read

Dormant Stem Cells May Hold Key to Restoring Sense of Smell

Researchers have created a 3D mouse organoid model to study how neurons in the nose regenerate, revealing that a type of stem cell once considered dormant may be crucial for repairing olfactory tissue. The team found that horizontal basal cells (HBCs), marked by KRT5, actively support new neuron generation alongside globose basal cells (GBCs).

Featured Genetics Neuroscience Psychology

·June 3, 2025·4 min read

Shared Genetic Signatures Found Across Psychiatric Disorders

Researchers have uncovered shared biological mechanisms across major psychiatric disorders by analyzing postmortem brain samples from the dorsolateral prefrontal cortex. Instead of looking at gene expression broadly, they zoomed in on the exon level—the building blocks that influence how proteins are made.

Featured Genetics Neurology Neuroscience

·June 2, 2025·6 min read

Blocking Brain Inflammation Molecule May Halt Alzheimer’s

A new study has uncovered a surprising culprit in the progression of Alzheimer’s disease: the immune molecule STING. Scientists found that STING, normally involved in defending the brain, becomes hyperactive with age, causing harmful inflammation and accelerating brain damage.

Featured Genetics Neuroscience

·June 2, 2025·6 min read

How Cocaine Hijacks the Brain

In a groundbreaking study, researchers have engineered fruit flies that voluntarily consume cocaine, creating the first fly model for cocaine addiction. Typically, flies avoid the drug due to its bitter taste, but by disabling their bitter-sensing receptors, scientists encouraged addictive behavior within just 16 hours of exposure.

Featured Genetics Neuroscience

·May 31, 2025·5 min read

One Molecule to Sleep and Wake: A New Brain Switch Discovered

Researchers studying the tiny roundworm C. elegans have uncovered a surprising mechanism by which a single brain signal controls both falling asleep and waking up. The chemical messenger FLP-11 activates a receptor called DMSR-1 in different neurons to either silence wakefulness or shut down sleep, acting as a biological on-off switch.

Featured Genetics Neurology Neuroscience

·May 30, 2025·7 min read

Blood Fat Links Found Between Heart Risk and Alzheimer’s

New research reveals complex relationships between blood lipid levels and the risk of developing Alzheimer’s disease, the most common form of dementia. While small dense LDL cholesterol—linked to heart disease—was associated with increased Alzheimer’s risk, other markers like ApoB48 were linked to reduced risk.

This shows a man, a woman, DNA, and a brain.

Featured Genetics Neurology Neuroscience

·May 30, 2025·5 min read

Common Gene Variant Doubles Dementia Risk, But Only in Men

New research reveals that men who carry two copies of a common genetic variant in the HFE gene are more than twice as likely to develop dementia, while women with the same variant are not affected. The variant, known as H63D, is linked to haemochromatosis and is present in about 1 in 36 people.

Neuroscience

·May 30, 2025·5 min read

Neuroscience and Genetics of ADHD and Neurodevelopment

A leading figure in molecular psychiatry shares how curiosity about DNA led to a career focused on unraveling the biological roots of neurodevelopmental conditions like ADHD. By bridging genetics, neuroscience, and psychiatry, their work has illuminated how variations in DNA and environmental influences shape brain development and behavior.

Brain Cancer Featured Genetics Neurology Neuroscience

·May 30, 2025·6 min read

Lab-Designed Peptide Targets Glioblastoma Stem Cells

A newly developed lab-designed molecule, JM2, may offer a promising therapy to combat glioblastoma recurrence by targeting the tumor’s most resilient cells. Researchers discovered that glioblastoma stem cells rely on the protein connexin 43’s interaction with microtubules—an interaction disrupted by JM2.

Featured Neuroscience

·May 29, 2025·5 min read

Modeling Brain’s Vesicle Cycle Unlocks Synaptic Secrets

A new computational model has mapped the brain’s vesicle cycle in unprecedented detail, providing fresh insight into how nerve cells communicate. Researchers collaborated to simulate how vesicles—tiny sacs that release neurotransmitters—operate within synapses.

Featured Genetics Neuroscience Psychology

·May 29, 2025·5 min read

Seasonal Sunlight Still Shapes Human Sleep

Despite modern lighting and lifestyle, human sleep patterns remain deeply influenced by seasonal changes in sunlight. New research reveals that our circadian rhythms track daylight shifts across seasons, impacting mood, sleep alignment, and overall health.

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Genetics

HIV Drugs Linked to Lower Alzheimer’s Risk

Dormant Stem Cells May Hold Key to Restoring Sense of Smell

Shared Genetic Signatures Found Across Psychiatric Disorders

Blocking Brain Inflammation Molecule May Halt Alzheimer’s

How Cocaine Hijacks the Brain

One Molecule to Sleep and Wake: A New Brain Switch Discovered

Blood Fat Links Found Between Heart Risk and Alzheimer’s

Common Gene Variant Doubles Dementia Risk, But Only in Men

Neuroscience and Genetics of ADHD and Neurodevelopment

Lab-Designed Peptide Targets Glioblastoma Stem Cells

Modeling Brain’s Vesicle Cycle Unlocks Synaptic Secrets

Seasonal Sunlight Still Shapes Human Sleep

AI Body Gap: Why Robots Need “Internal Feelings” to be Safe

Wetware AI: Living Brain Cells Trained to Run Chaos Math

Mapping the Brain’s Internal Stopwatch

Individual Cone Cells Create Our Sharpest Sight

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