Glioblastoma brain cancer cells that are more resistant to radiation therapy have higher levels of purines. Reducing the level of purines made the cancer cells more sensitive to radiation.
Glioblastoma brain cancer originates from a pool of stem cells that can be a significant distance away from where the tumor eventually forms.
An oncogene believed to be responsible for glioblastoma brain cancer has been identified. AVIL, a gene that normally helps cells to maintain their shape and size, can shift into overdrive, causing cancer cells to form and spread. Blocking the gene's activity completely destroyed glioblastoma cancer cells in mouse models, but did not have any effect on healthy cells. The findings provide potential new treatment avenues for the deadly brain cancer.
Focused ultrasound treatments show promise in the fight against glioblastoma brain cancer. Sonodynamic therapy may also help treat other difficult-to-treat cancers.
Trifluoperazine, a dopamine receptor antagonist commonly prescribed for schizophrenia, used in combination with radiation therapy delays the growth of glioblastoma brain tumors and prolongs survival for brain cancer.
Combining niacin, or vitamin B3, with chemotherapy, helped slow the progression and increase life span in mouse models of glioblastoma.
A new brain chip allows multiple simultaneous drugs to be administered directly to glioblastoma brain cancer tumors.
Extra DNA is critical for maintaining cancer-causing gene activation and supporting the cancer cell's ability to survive.
Surfen, a compound molecule used for drug delivery of insulin could block tumor growth for patients with glioblastoma brain cancer.
Novel biomarkers for glioblastoma brain cancer have been identified in bodily fluids. The discovery may lead to a new, simple, non-invasive blood test to detect brain cancer in the future.
After a single session of transcranial electrical stimulation (tES), researchers noted a significant reduction in blood flow to brain tumors. However, there were no alterations in blood flow or activity in the rest of the brain. The technique may be helpful in the treatment of brain cancers such as glioblastoma.
Teriflunomide, a drug commonly used to treat multiple sclerosis, shows promise for the treatment of glioblastoma when coupled with targeted cancer therapies.
