Non-coding DNA located outside chromosomes may help drive glioblastoma
Extra DNA is critical for maintaining cancer-causing gene activation and supporting the cancer cell's ability to survive.... Read More...
GBM
Existing drug could treat aggressive brain cancer
Surfen, a compound molecule used for drug delivery of insulin could block tumor growth for patients with glioblastoma brain cancer.... Read More...
Glioblastoma brain cancer could be diagnosed with simple blood test in future
Novel biomarkers for glioblastoma brain cancer have been identified in bodily fluids. The discovery may lead to a new, simple, non-invasive blood test to detect brain cancer in the future.... Read More...
Non-invasive electrical stimulation alters blood flow in brain tumors
After a single session of transcranial electrical stimulation (tES), researchers noted a significant reduction in blood flow to brain tumors. However, there were no alterations in blood flow or activity in the rest of the brain. The technique may be helpful in the treatment of brain cancers such as glioblastoma.... Read More...
Adding MS drug to targeted cancer therapy may improve glioblastoma outcomes
Teriflunomide, a drug commonly used to treat multiple sclerosis, shows promise for the treatment of glioblastoma when coupled with targeted cancer therapies.... Read More...
Study hints at why an aggressive form of brain cancer is hard to treat
Genetics and microenvironment influence the frequency of glioblastoma cells. Researchers provide a new blueprint for glioblastoma, integrating the malignant cell programs, cancer cell plasticity, and modulation by genetic drivers. The findings shed light on why this form of cancer is so hard to treat effectively.... Read More...
Scientists track brain tumor turncoats with advanced imaging
Advanced imaging techniques visualize macrophages in brain tumors in mouse models of glioblastoma. ... Read More...
Study finds macrophages’ pathway to nurture PTEN-deficient glioblastoma: Mouse study
PTEN deficiency drives an increased expression of LOX. LOX attracts macrophages which protect gliobastoma brain cancer cells and provide growth factor support for the tumor, a new mouse study reveals.... Read More...
Pairing of glutamine-targeting drug and ketogenic diet fights glioblastoma in mice
Combining an antibiotic drug that targets glutamine with the ketogenic diet helps kill glioblastoma cancer cells, reversing symptoms of the disease and improving survivability in mouse models.... Read More...
Scientists ‘reverse engineer’ brain cancer cells to find new targets for treatment
Using CRISPR-Cas9 gene editing, researchers identified actionable pathways responsible for the growth of glioblastoma stem cells. By reverse engineering brain cancer cells, multiple potential new targets for cancer treatments have been uncovered.... Read More...
New glioblastoma vaccine shows promising results in phase Ib clinical trial
A new vaccine for glioblastoma brain cancer suspends tumor growth and is well tolerated by patients, according to the results of an early phase clinical trial.... Read More...
Immunotherapy Can Be Effective in Treating People with Recurrent Glioblastoma
Researchers report administering immunotherapy treatment prior to surgery for those with recurring glioblastoma brain cancer is more effective that using the treatment after surgery.... Read More...