Scientists track brain tumor turncoats with advanced imaging
Advanced imaging techniques visualize macrophages in brain tumors in mouse models of glioblastoma. ... Read More...
GBM
Study finds macrophages’ pathway to nurture PTEN-deficient glioblastoma: Mouse study
PTEN deficiency drives an increased expression of LOX. LOX attracts macrophages which protect gliobastoma brain cancer cells and provide growth factor support for the tumor, a new mouse study reveals.... Read More...
Pairing of glutamine-targeting drug and ketogenic diet fights glioblastoma in mice
Combining an antibiotic drug that targets glutamine with the ketogenic diet helps kill glioblastoma cancer cells, reversing symptoms of the disease and improving survivability in mouse models.... Read More...
Scientists ‘reverse engineer’ brain cancer cells to find new targets for treatment
Using CRISPR-Cas9 gene editing, researchers identified actionable pathways responsible for the growth of glioblastoma stem cells. By reverse engineering brain cancer cells, multiple potential new targets for cancer treatments have been uncovered.... Read More...
New glioblastoma vaccine shows promising results in phase Ib clinical trial
A new vaccine for glioblastoma brain cancer suspends tumor growth and is well tolerated by patients, according to the results of an early phase clinical trial.... Read More...
Immunotherapy Can Be Effective in Treating People with Recurrent Glioblastoma
Researchers report administering immunotherapy treatment prior to surgery for those with recurring glioblastoma brain cancer is more effective that using the treatment after surgery.... Read More...
The Hitchhiker’s Guide to Defeating Glioblastoma
Researchers have developed a new approach that uses microRNA in combination with chemotherapy to help treat glioblastoma brain cancer. In preclinical models, the approach increases survival of the deadly brain cancer five fold.... Read More...
A Patient’s Sex Matters When it Comes to Brain Cancer
Researchers report our gender can determine longevity and response to treatment for glioblastoma brain cancer. The study reports male survival is determined by genes that control cell division, where as female survival is often determine by genes that regulate the ability of cancer cells to migrate to different brain areas.... Read More...
Sex Differences Identified in Glioblastoma Brain Cancer
A new study reveals distinct molecular differences in signatures of glioblastoma brain cancer between men and women. Researchers report current treatments for the brain cancer are more effective in women than in men. The findings could help to tailor treatments aimed at the different sexes and improve survival.... Read More...
Drug Discovery Could Halt Brain Cancer Spread
Researchers detail the use of a drug that may help block the way glioblastoma brain cancer cells respond to fluid flow. The finding could lead to stopping glioblastoma from spreading. ... Read More...
Brain Cancer Atlas Created
A new brain cancer atlas maps out comprehensive, visually rich information about the anatomical and genetic bases of glioblastoma, researchers report.... Read More...
A Potential Achilles Heel in Brain Cancer
A new study in PNAS reports blocking the expression of MDA-9/Syntenin forces glioma stem cells to lose their ability to induce protective autophagy.... Read More...