Irisin, a hormone secreted by muscles during exercise, improved cognitive function and lowered levels of inflammation in mouse models. The findings have implications for the development of treatments for Alzheimer's and other neurodegenerative diseases.
Researchers report the brains of people with Alzheimer's disease contain less of the exercise related hormone called irisin. Boosting levels of irisin in the brain could slow the progression of the neurodegenerative disease.
Researchers report physical exercise failed to promote antidepressant-like effects in mice genetically engineered to express a human genetic variation in the gene BDNF.
Researchers isolated a protein which is increased during indurance exercise and gave it to non-exercising mice. The protein turned on genes which promote brain health and encouage new neurons to grow.