Latest

entorihinal cortex

·May 18, 2026·8 min read

Parkinson’s Drug Restores Memories in Alzheimer’s

Severe dopamine dysfunction in the entorhinal cortex is a primary, hidden mechanism behind Alzheimer's-related memory impairment. Researchers found that dopamine levels in this vital memory gateway drop to less than 20% of normal, causing localized neurons to stop encoding memories altogether.

Featured Neuroscience

·October 3, 2025·9 min read

How the Brain’s GPS System Falters With Age

Spatial memory — the ability to recall “where” — is one of the first cognitive skills to decline in aging and a hallmark of dementia. Researchers found that in older mice, grid cells in the medial entorhinal cortex, which act like the brain’s GPS, became unstable and less precise.

Featured Neuroscience

·September 30, 2022·4 min read

Superager Brains Contain ‘Super Neurons’

Neurons in the memory-associated entorhinal cortex of super-agers are significantly larger than their cognitively average peers, those with MCI, and even in people up to 30 years younger. Additionally, these neurons contained no signs of Tau, a hallmark of Alzheimer's disease.