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endothelial cells

·December 17, 2022·5 min read

Why Does the Alzheimer’s Brain Become Insulin-Resistant?

Insulin binding receptors are predominantly located in the microvessels within the blood-brain barrier. In patients with Alzheimer's, the abundance of these receptors is decreased. This decrease could lead to the loss of insulin response in the Alzheimer's brain.

Featured Neuroscience

·June 24, 2019·3 min read

Certain cells secrete a substance in the brain that protects neurons

Vascular cell loss results in neuron loss, researchers report. However, pericytes secrete a substance that helps protect neurons, even when vascular cell degeneration begins to occur.

Featured Neurology Neuroscience Open Neuroscience Articles Psychology

·May 7, 2019·5 min read

Everyday stress may boost blood vessel dysfunction in people with depression

Exposure to everyday stressors may result in impairments in endothelial function for patients with major depressive disorder. The findings reveal a possible reason for the association between stress, depression and an increased risk of cardiovascular disease.

Featured Neurology

·January 16, 2018·4 min read

High Salt Diet Produces Dementia: Mouse Study

Researchers reveal high salt intake reduces resting cerebral blood flow and can contribute to dementia in mice.

Featured Genetics Neurology Open Neuroscience Articles

·November 10, 2017·4 min read

Biomarker May Predict Early Alzheimer’s

Researchers discover the DAG peptide can recognize specific protein elevation in brain blood vessels of both mouse models and humans with Alzheimer's disease.

Featured Neuroscience Open Neuroscience Articles

·November 8, 2017·4 min read

A Recipe to Make a Human Blood-Brain Barrier

Researchers have defined a process that can help to create more realistic human blood-brain barriers in a dish.

Brain Cancer Featured Genetics Neurology Open Neuroscience Articles

·August 2, 2017·5 min read

Molecules That May Help Prevent Brain Tumor Development Identified

Researchers discover key elements associated with tumor cells binding to blood vessels. The findings could help develop new treatments to halt the development of brain tumors.

Featured Genetics Neurology Open Neuroscience Articles

·May 15, 2017·4 min read

Stem Cell Transplants May Advance ALS Treatment By Repairing Blood-Spinal Cord Barrier

According to researchers, bone marrow stem cell transplants helped repair damage to the blood spinal cord barrier in mouse models of ALS. This helped improve motor functions and nervous system conditions.

Featured Neuroscience Neuroscience Videos

·April 11, 2017·5 min read

Tracing the Origin of Blood-Brain Barrier ‘Sentry Cells’

According to researchers, a population of cells that help protect the brain from disease are not immune cells, but endothelial cells.

Featured Neuroscience

·February 5, 2017·5 min read

With Mini-Vessels, Mini-Brains Expand Research Potential

Mini-brains that are able to grow blood vessels are paramount for future investigation of neurological disorders, researchers report.

Image shows human neuronal cells can be cultured from aged adult brain.

Featured Genetics Neuroscience Open Neuroscience Articles

·January 17, 2017·5 min read

First Cell Culture of Live Adult Human neurons Shows Potential of Brain Cell Types

Researchers successfully grew adult human neurons from tissue donated from surgery patients. The researchers were able to identify at least 5 brain cell types and the potential proteins each cell could make.