Study explains how an overexpression of the RCAN1 gene may cause intellectual disabilities in people with Down syndrome. Read More
Sleep disruptions are common features of Fragile X syndrome, Williams syndrome, and Down syndrome. The disruption of sleep in these neurodevelopmental disorders appears to be linked to language development. The longer children with neurodevelopmental disorders slept, the more words they knew. Read More
Using stem cells from candidates with Down syndrome to create an organoid, and employing mouse models, researchers pinpoint a gene linked to memory impairments and cognitive problems in Down syndrome. Inhibiting the OLIG2 gene leads to cognitive and memory improvements in mouse models of Down. Researchers hope their findings lead to an in utero treatment that targets the gene and helps reverse abnormal brain development. Read More
A new study reports that while an afternoon naps are beneficial for memory and learning in typically developing children, in those with Down syndrome, napping may increase memory loss. Read More
Researchers have successfully transplanted human brain cells into mouse brains and watched how they grow to form networks. The technique could be used to study a range of neurological conditions, the researchers report. Read More
Researchers report extra copies of genes on chromosome 21 increase Alzheimer's like pathology and cognitive impairment in mouse models of Down syndrome. The findings provide insight into early onset Alzheimer's in those with Down syndrome. Read More
A new study provides contrary evidence to popular belief and states people with congenital intellectual disabilities are sensitive to placebo-like effects. Read More
Researchers track changes over decades and break down by racial groups the number of people diagnosed with Down syndrome. Read More
According to researchers, the benefits of having children later in life outweigh possible biological risks for the offspring. Read More
Abnormalities are linked to axonal dysfunctions and neurodegeneration in Alzheimer's disease and Down syndrome, a new study reports. Read More
Researchers have identified alterations in neural circuitry that impact cerebral cortex pathology. These alterations could be key to cognitive deficits in Down syndrome. Read More
A new study of gene activity in the brains of people with Down syndrome reveals the formation of white matter is affected throughout life. Read More
