Researchers shed new light on how remylination fails in multiple sclerosis. The study reports a drug, currently being studied as a cancer therapy, can alter the key signaling cascades that result in demylination associated with MS.
12 genes associated with familial multiple sclerosis have been identified. The findings provide a molecular rationale for the chronic inflammation, demyelination and neurodegeneration associated with MS. Identifying new genetic targets could help with the development of novel treatments to prevent multiple sclerosis in those with a genetic risk.
A new study in Scientific Reports concludes human herpesvirus 6 may impair the brain's ability to repair itself in demylination diseases, such as multiple sclerosis. HHV-6 is the most common human herpes virus, with an estimated 80% of people being exposed to infection during childhood. Researchers found the virus produces a protein that can impair the ability of brain cells to repair damaged myelin.
A new study reports people can show early symptoms of multiple sclerosis up to five years before full onset of the disease.
Researchers report the Zika virus may also be tied to an automimmune disease that attacks myelin similar to multiple sclerosis.