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demylination

·April 10, 2025·4 min read

Exercise Depletes Brain Myelin, But It Recovers Fully

New research shows that running a marathon can cause a temporary reduction in brain myelin, the fatty substance that insulates neurons and supports efficient communication. This decrease, observed in regions related to motor coordination and sensory processing, appears to result from the body using myelin lipids as an energy reserve when other fuels are exhausted.

This shows a cross section of a spinal cord

Featured Neurology Neuroscience

·October 23, 2021·5 min read

Fighting Multiple Sclerosis With Cold

Cold exposure therapies could help alleviate symptoms of multiple sclerosis by depriving the immune system of its energy.

Featured Neurology Neuroscience Open Neuroscience Articles

·March 29, 2021·7 min read

How the Brain Inhibits Remyelination in MS, and How to Treat It

Researchers shed new light on how remylination fails in multiple sclerosis. The study reports a drug, currently being studied as a cancer therapy, can alter the key signaling cascades that result in demylination associated with MS.

Featured Genetics Neurology Neuroscience

·October 7, 2019·3 min read

Surprise contributor to multiple sclerosis identified

Oligodendrocyte progenitor cells (OPCs) actively contribute to neuroinflammation associated with multiple sclerosis.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·June 6, 2019·3 min read

12 genes at the root of multiple sclerosis identified

12 genes associated with familial multiple sclerosis have been identified. The findings provide a molecular rationale for the chronic inflammation, demyelination and neurodegeneration associated with MS. Identifying new genetic targets could help with the development of novel treatments to prevent multiple sclerosis in those with a genetic risk.

Image shows an electron micrograph of HHV-6 also includes a labeled insert of the mature virus particle.

Featured Neurology Open Neuroscience Articles

·July 10, 2017·5 min read

Hidden Herpes Virus May Play Role in Multiple Sclerosis and Other Brain Disorders

A new study in Scientific Reports concludes human herpesvirus 6 may impair the brain's ability to repair itself in demylination diseases, such as multiple sclerosis. HHV-6 is the most common human herpes virus, with an estimated 80% of people being exposed to infection during childhood. Researchers found the virus produces a protein that can impair the ability of brain cells to repair damaged myelin.