Latest

CRISPR-Cas9

Brain Cancer Featured Genetics Neuroscience

·April 10, 2023·3 min read

Identifying Cancer Genes’ Multiple Personalities

A new method using the gene-editing tool CRISPR-Cas9 has been developed to model liver cancer tumor subtypes caused by mutations in the same genes. By targeting a single section of the mouse gene, Ctnnb1, researchers were able to produce two distinct tumor subtypes, enhancing protein activity to promote tumor growth, which could allow for the development of new therapeutic interventions in the future.

Featured Genetics Neurology Neuroscience

·September 22, 2022·5 min read

Pigs With Gene Defect Provide New Perspectives for the Treatment of Alzheimer’s

New research in cloned pigs with a mutation of the SORL1 sheds light on Alzheimer's development. The findings could pave the way for new treatments for the neurodegenerative disorder.

Featured Neurology Neuroscience

·October 5, 2021·4 min read

Study Detects Origins of Huntington’s Disease in Two-Week-Old Human Embryos

Synthesizing a human embryo from stem cells and using gene editing to insert the Huntingtin gene, researchers found the mutation affected the size of germ layers compared to the control embryos. Findings suggest Huntington's disease may be a neurodevelopmental disorder that presents as a neurodegenerative disease later

Featured Neuroscience

·August 16, 2021·2 min read

How Testosterone Works in the Brain

A new study is set to discover precisely which aspects of social behavior androgens regulate and how they do it.

Featured Genetics Neuroscience

·June 12, 2019·7 min read

Using gene editing, neuroscientists develop a new model for autism

Using CRISPR gene editing, researchers introduce the SHANK3 gene variant into macaque monkeys. SHANK3 has previously been linked to autism in humans. The monkeys with the SHANK3 mutations exhibited behavioral traits and brain activity patterns similar to those seen in humans on the autism spectrum, Researchers hope the new model will facilitate new avenues of research for ASD.

This shows a child looking at a DNA double helix

Autism Featured Genetics Neuroscience

·May 24, 2019·4 min read

New approaches to study the genetics of autism may lead to new therapies

Researchers will present their latest findings regarding genes associated with autism spectrum disorder in an upcoming meeting.

Brain Cancer Featured Genetics Neuroscience Open Neuroscience Articles

·April 16, 2019·4 min read

Scientists ‘reverse engineer’ brain cancer cells to find new targets for treatment

Using CRISPR-Cas9 gene editing, researchers identified actionable pathways responsible for the growth of glioblastoma stem cells. By reverse engineering brain cancer cells, multiple potential new targets for cancer treatments have been uncovered.

Featured Genetics

·January 13, 2019·5 min read

CRISPR Repurposed to Develop Better Antibiotics

Researchers re-purposed CRISPR gene editing technology to study genes targeted by particular antibiotics. The study sheds light on how pharmacologists can improve existing antibiotics and develop new ones.

Autism Featured Genetics Neuroscience Psychology

·November 7, 2018·4 min read

Unraveling a Genetic Network Linked to Autism

Using CRISPR techniques, researchers have uncovered a genetic network linked to autism.

Featured Genetics Neuroscience

·November 1, 2018·5 min read

RNA Changes Aid Memory and Learning Process

The most common messenger RNA modification in mammals helps coordinate nerve cell response to memory inducting stimulus, a new study reveals.

Featured Genetics Neurology Open Neuroscience Articles

·October 9, 2018·5 min read

New Alzheimer’s Biomarker Identified with Help of CRISPR

With the aid of CRISPR gene editing techniques, researchers have identified a new biomarker for Alzheimer's disease. The study reports a deficiency of the protein STIM1 could be implicated in the sporadic version of the neurodegenerative disease.