Researchers reveal the role hundreds of miRNAs appear to play in modulating circadian rhythm.
Pigment-dispersing factor, a signalling protein that helps the brain keep track of time, also helps to regulate memory formation.
Two small molecules, KL101 and TH301, are the first compounds that selectively target circadian clock components CRY1 and CRY2.
Deleting the circadian rhythm-associated BMAL1 gene in animal models, researchers discovered tissue continued to follow a 24-hour rhythm, even in the absence of external stimuli that can influence the cycle.
The strength of the brain's global signal fluctuation decreases as the day progresses.
Study reveals how certain genetic mutations can shorten the timing of the circadian clock, making some people extreme "morning larks" because their internal clock operates on a 20-hour cycle, as opposed to a 24-hour cycle.
Chronobiologists warn changing to daylight savings can have serious effects on both brain and general health. The change in time during spring was linked to a 24% increase in severe cardiovascular events in women. Researchers also noted the sudden change in time alters circadian rhythms, reduces the production of natural melatonin, impacts cognitive function, and may also foster tumor growth.
Study shows how circadian clock mechanisms boost our ability to maintain our bodies when we are most active.
Removing BMAL1, a gene commonly associated with circadian rhythm, makes macrophages more effective and the body more resistant to pneumonia.
Seasonal affective disorder (SAD) affects over 10 million people in the US. Find out the symptoms and treatment options available.
Neuropsin is expressed in the hair follicles of mice and synchronizes the skin's circadian clock, independent of the brain or eyes.
Study reveals the function of specific immune cells, well documented as playing a significant role in gut health, is directly controlled by our circadian clock.
