Findings shed light on the mechanisms underlying brain damage in microgravity.
Researchers report Alzheimer's disease and other neurodegenerative disorders can be confirmed in living patients by specific biomarkers in cerebrospinal fluid.
Findings support the current theory that sleep may be involved in the regulation of metabolic waste clearance and highlights the link between sleep and fluid flow in the human brain.
Long duration microgravity exposure caused expansions in the combined brain and cerebrospinal fluid volumes in astronauts.
Computational model provides caregivers and doctors a better understanding of the potential outcomes for a young child who suffers from a head injury as a result of abuse.
Following a stroke, dysfunction in the glymphatic system causes cerebrospinal fluid to flood the brain, drowning neurons, and triggering cerebral edema.
Study reveals as we sleep, cerebrospinal fluid pulses in the brain in rhythmic patterns.
Ceramide exposure impairs the ability for neurons to make energy by directly damaging mitochondria. Additionally, ceramides force neurons to rapidly uptake glucose in order to provide cellular energy.
Retroviruses may be a missing causal link in diseases like ALS, multiple sclerosis and schizophrenia.
Damaged olfactory neurons as a result of air pollution may contribute to altered cerebrospinal fluid flow and turnover, acting as a potential mechanism for the development of neurodegenerative diseases.
Researchers have identified average levels of biological and anatomical brain changes associated with Alzheimer's disease over thirty years before symptoms appear. In those with genetic risk factors for Alzheimer's, researchers found changes in cognitive performance up to 15 years before becoming symptomatic. Changes in Tau levels in the cerebral spinal fluid appeared up to 34 years before dementia symptoms occurred, and physical changes to the medial temporal lobe were apparent up to 9 years before cognitive impairment was apparent.
A new study reports the atrophy of brain lesion volume predicts the development of more physical disabilities associated with multiple sclerosis.
