Reducing dietary levels of methionine can slow the onset and progression of inflammatory and autoimmune diseases, such as multiple sclerosis, in those with high-risk factors.
The fetal gut has far better developed immune capabilities than previously thought. The findings could help develop new maternal vaccines and provide early insight into potential autoimmune disorders, which may occur later in life.
A newly discovered subset of dendritic cells have been implicated in sexually transmitted HIV infection. The CD11c+ dendritic cells are found in human genital tissue at the epithelial level. They are the first immune cells to interact with the HIV virus. The cells directly transfer the virus to CD4 T cells, making them key drivers in HIV transmission.
Exposure to viral infections in the brain during childhood has been linked to an increased risk of developing multiple sclerosis later in life.
Vitamin D causes dendritic cells to produce more CD31, hindering the activation of T cells. The study sheds light on how vitamin D deficiency regulates the immune system and can lead to autoimmune diseases, like multiple sclerosis.
Autoreactive cytotoxic CD8 T cells have been detected in people with narcolepsy type one. The finding suggests levels of the T-cell reactivity, combined with specific gene expression, may spur on the development of NT1.
Researchers report defects in the Ets1 gene is linked to characteristics associated with systemic lupus erythematosus immune abnormalities.
A new study reports T cells are activated in the intestines and migrate to the brain, causing an inflammatory cascade that may lead to multiple sclerosis. Researchers say the gut microbiome may play a more significant role in the development and progression of MS than previously believed.
A new study reveals how autophagy in certain immune cells can lead to the immune system attacking the central nervous system. The findings have implications for the treatment of autoimmune diseases, like multiple sclerosis.
MIT researchers report mothers who contract severe infections during pregnancy face higher autism risks in their children. However, ASD risks could be reduced by blocking the function of certain strains of bacteria found in the mother's gut.
Using a compound to block the immune response significantly reduces further brain injury after stroke, a new report claims.
