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Featured Neuroscience Open Neuroscience Articles

·June 12, 2020

Inhibitory interneurons in hippocampus excite the developing brain

GABAergic interneuron excitation is essential for network activity in the hippocampus of the fetal brain. Read More

Featured Neurology Neuroscience

·June 9, 2020

Noise-inducing neurons shut down memories in Alzheimer’s

In mouse models of Alzheimer's disease, active neurons still encode memory, and a group of active neurons encodes novel environmental information. The signal of the novelty containing neurons causes a superimposition disturbing the signal of memory encoding neurons. Read More

This shows the outline of a head and a city scape

Featured Neuroscience

·April 6, 2020

Memory cells that help us interpret new situations identified

Hippocampal neurons that store abstract memories of prior experiences activate when new, but similar events take place. Read More

Featured Genetics Neuroscience Open Neuroscience Articles

·March 9, 2020

Brain-doping produced by your own body

Cognitive challenges trigger a slight oxygen deficit in hippocampal pyramidal neurons. This increases the production of erythropoietin (Epo) and its receptors in the active neurons, stimulating neighboring precursor cells to form new neurons and enhancing connectivity. Read More

Featured Neuroscience Open Neuroscience Articles

·February 6, 2020

Synchronization of memory cells critical for learning and forming memories

Hippocampal neurons involved in Pavlovian learning shift their behavior and become more synchronized when a memory is being formed. The findings shed new light on the neurobiological mechanisms of memory and learning. Read More

This shows the location of the amygdala and hippocampus in the brain

Featured Neuroscience

·October 2, 2019

Male/female differences in the development of brain hubs involved in memory and emotion

A new neuroimaging study reveals sex-based differences in the development of the hippocampus and amygdala. The findings may shed light on sex-based differences in the emergence of mental health disorders the occur during adolescence and early adulthood. Read More

Featured Neurology Neuroscience

·October 1, 2019

Study provides possible explanation of how a seizure is able to spread through the brain

A new study implicated interneurons and pyramidal cells in the ability of a seizure to spread through the brain. Read More

Featured Neuroscience

·September 23, 2019

Critical role of brain circuits in improving learning and memory revealed

A newly identified neural network in the hippocampal formation plays a critical role in memory and object-location learning. The findings are highly relevant to learning and memory disorders, including Alzheimer's disease. Read More

Featured Neurology Neuroscience

·August 29, 2019

Lack of oxygen doesn’t kill infant brain cells, as previously thought

A lack of oxygen as a result of preterm birth does not cause hippocampal neurons to die but does impair hippocampal development. Hypoxia causes hippocampal cells to fail to mature normally, causing a reduction in long-term potentiation and impaired learning. Read More

Featured Neuroscience

·August 24, 2019

How memories form and fade

Stable memories are encoded by teams of neurons firing in synchrony, providing redundancy that enables the memory to persist over time. Read More

Featured Neuroscience

·August 12, 2019

Negative memory storage affects depression symptoms

Enhanced reactivation of negative memory engrams may be an important cellular mechanism behind the cognitive symptoms of depression. Read More

Featured Neuroscience

·July 1, 2019

Sleep readies synapses for learning

Hippocampal neurons become longer and stronger following a period of sleep deprivation. The study supports the hypothesis that sleep may weaken synapses, which are strengthened from learning, allowing for learning to occur after waking. Read More

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