Researchers found compelling molecular evidence suggesting that bipolar disorder and schizophrenia, traditionally viewed as distinct conditions, may have more similarities than previously thought. By examining thousands of proteins present at synapses in the brains of patients with each disorder, they found changes that were remarkably alike. The team also discovered similar biochemical alterations in mice with a mutated gene linked to both conditions. The study reveals the shared molecular roots of these conditions and points to the synapse as a critical area of study for psychiatric disorders.
