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          brain organoids

          This shows neurons.
          FeaturedNeuroscience
          ·July 10, 2025·7 min read

          Lab-Grown Neurons Reach Unprecedented Diversity

          Researchers have created over 400 distinct types of human nerve cells in vitro, vastly expanding the diversity available for neuroscience research. By systematically combining genetic engineering with morphogen signaling molecules, they mimicked the intricate variety of neurons found in the brain.
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          This shows a neuron.
          FeaturedNeurologyNeurosciencePain
          ·April 13, 2025·10 min read

          Lab-Grown Nerve Circuit Recreates Human Pain Pathway

          Researchers have recreated the human ascending sensory pathway in a lab dish, using organoids that model the key brain and spinal cord regions responsible for transmitting pain. This breakthrough allows scientists to observe how pain signals travel from peripheral neurons to the brain for the first time outside the body.
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          This shows the trunk organoid.
          FeaturedGeneticsNeuroscience
          ·December 19, 2024·4 min read

          Notochord Guides Neural and Spinal Formation

          Scientists have developed human stem cell models containing the notochord, a critical tissue that guides spine and nervous system formation during embryonic development. Using precise chemical signals inspired by natural processes in chicken, mouse, and monkey embryos, the researchers successfully coaxed human stem cells to form a notochord and a miniature trunk-like structure. This innovation mirrors key features of human development and could advance the study of spine-related birth defects and conditions like intervertebral disc degeneration.
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          This shows a neuron.
          FeaturedNeuroscience
          ·December 17, 2024·4 min read

          Lab-Grown Neurons Mimic Brain Networks, Exhibit Neuroplasticity

          Researchers have developed lab-grown neurons that behave more like real brain networks, advancing the study of learning and memory. Using microfluidic devices, the neurons formed diverse and functional networks, resembling those seen in living nervous systems.
          Read More
          This shows mitochondria.
          FeaturedGeneticsNeuroscience
          ·December 14, 2024·3 min read

          Mini-Brains Reveal New Insights Into Mitochondrial Brain Disorders

          Researchers have created mini-brains to study how mitochondrial failure impacts brain cells, opening new possibilities for treating severe conditions like epilepsy. These brain organoids mimic real disease processes, allowing scientists to observe mitochondrial dysfunction and test potential treatments.
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          This shows the glioblastoma model.
          Brain CancerFeaturedNeurologyNeuroscience
          ·December 9, 2024·6 min read

          Lab-Grown Tumor Models Mirror Glioblastoma Treatment Response

          Glioblastoma organoids, lab-grown replicas of a patient’s tumor, accurately predict how the tumor responds to CAR T cell therapy. This breakthrough allows real-time testing of therapies, showing that responses in the organoid closely mirror those in the patient.
          Read More
          This shows a brain and DNA.
          AutismFeaturedNeuroscience
          ·October 24, 2024·6 min read

          Stem Cell Mini-Brains Unlock Insights into Autism

          Researchers have created "mini-brains" using stem cells from patients with a rare form of autism, allowing them to study brain development in detail. These organoids revealed how a genetic mutation in MEF2C disrupts the balance between excitatory and inhibitory neurons, leading to autism.
          Read More
          This shows neurons.
          FeaturedNeurologyNeuroscience
          ·October 15, 2024·4 min read

          Mini Brains Uncover Treatment Leads for Lewy Body Dementia

          Lewy body dementia (LBD) is a challenging-to-diagnose neurodegenerative disease with symptoms similar to both Parkinson’s and Alzheimer’s diseases, including hallucinations, cognitive issues, and movement disorders. To study LBD’s progression, researchers developed mini brain models from LBD patient stem cells, replicating key disease characteristics seen in human brains. These models helped identify four promising drugs that may inhibit alpha-synuclein buildup, a key protein associated with LBD.
          Read More
          This shows cells.
          FeaturedNeuroethicsNeuroscience
          ·June 20, 2024·4 min read

          Organoids and Embryo Models: Redefining Human Individuality?

          Advances in organoids and embryonic models raise questions about human individuality. A new study argues these models can reinforce, not weaken, the concept of human individuality when viewed through personhood and sentience frameworks. Researchers emphasize that current technologies are far from achieving personhood in embryo models or organoids. The ethical focus should remain on the wellbeing of actual persons and sentient beings.
          Read More
          This shows neurons.
          FeaturedGeneticsNeurologyNeuroscience
          ·May 14, 2024·6 min read

          Mini-Brains from Stem Cells Provide Hope for Alzheimer’s Diagnosis

          Researchers developed tiny "mini-brains" from stem cells to help diagnose and treat Alzheimer’s disease. These mini-brains, created from human blood, accurately reflect the pathology of Alzheimer’s on a smaller scale. This innovative technology could revolutionize healthcare, especially for remote communities, by providing a simpler way to diagnose neurological conditions.
          Read More
          This shows the lab grown networks.
          FeaturedNeuroscience
          ·April 10, 2024·4 min read

          Bridging Brain Circuits with Lab-Grown Neural Networks

          Researchers successfully connected lab-grown brain tissues, mimicking the complex networks found in the human brain. This novel method involves linking “neural organoids” with axonal bundles, enabling the study of interregional brain connections and their role in human cognitive functions.
          Read More
          This shows a computer chip.
          FeaturedNeuroscience
          ·December 12, 2023·4 min read

          Innovative Brain Cell Chips Unlock New Horizons in Speech Recognition

          In a revolutionary study, researchers created a hybrid system called Brainoware, which integrates human brain cell networks, or organoids, with a computer chip. This innovative setup demonstrates capabilities in processing, learning, and memory, and has achieved basic speech recognition skills by decoding audio clips of Japanese vowels.
          Read More
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          This shows a brain surrounded by fruits.

          Promise of Reward Changes How We Pay Attention

          This shows a woman with two french bulldogs.

          Do Dog Faces Shape Behavior?

          This shows an adult and a child.

          How Kids Learn What Emotions Really Mean

          This shows an older man on an exercise bike in a hospital. A nurse is at his side. On the cycle is a monitor with a brain game.

          Cycling Boosts Brain Function in Parkinson’s Disease

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