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brain organoids

·September 22, 2025·5 min read

Mini Brains Expose Neural Signatures of Schizophrenia and Bipolar

For the first time, lab-grown mini brains have revealed how neurons misfire in schizophrenia and bipolar disorder. Using machine learning to analyze electrical activity, researchers identified distinct firing patterns that served as biomarkers, distinguishing patient-derived organoids from healthy ones with over 90% accuracy.

Featured Neuroscience

·August 14, 2025·4 min read

First “Microwave Brain” Chip Merges Ultrafast Data and Wireless Signals

Researchers have built the first “microwave brain” chip capable of processing both ultrafast data and wireless communication signals at once. By harnessing analog, nonlinear microwave physics instead of conventional digital circuitry, the chip can decode radio signals, track radar targets, and classify high-speed data streams in real time.

Featured Neuroscience

·July 10, 2025·7 min read

Lab-Grown Neurons Reach Unprecedented Diversity

Researchers have created over 400 distinct types of human nerve cells in vitro, vastly expanding the diversity available for neuroscience research. By systematically combining genetic engineering with morphogen signaling molecules, they mimicked the intricate variety of neurons found in the brain.

Featured Neurology Neuroscience Pain

·April 13, 2025·10 min read

Lab-Grown Nerve Circuit Recreates Human Pain Pathway

Researchers have recreated the human ascending sensory pathway in a lab dish, using organoids that model the key brain and spinal cord regions responsible for transmitting pain. This breakthrough allows scientists to observe how pain signals travel from peripheral neurons to the brain for the first time outside the body.

Featured Genetics Neuroscience

·December 19, 2024·4 min read

Notochord Guides Neural and Spinal Formation

Scientists have developed human stem cell models containing the notochord, a critical tissue that guides spine and nervous system formation during embryonic development. Using precise chemical signals inspired by natural processes in chicken, mouse, and monkey embryos, the researchers successfully coaxed human stem cells to form a notochord and a miniature trunk-like structure. This innovation mirrors key features of human development and could advance the study of spine-related birth defects and conditions like intervertebral disc degeneration.

Featured Neuroscience

·December 17, 2024·4 min read

Lab-Grown Neurons Mimic Brain Networks, Exhibit Neuroplasticity

Researchers have developed lab-grown neurons that behave more like real brain networks, advancing the study of learning and memory. Using microfluidic devices, the neurons formed diverse and functional networks, resembling those seen in living nervous systems.

Featured Genetics Neuroscience

·December 14, 2024·3 min read

Mini-Brains Reveal New Insights Into Mitochondrial Brain Disorders

Researchers have created mini-brains to study how mitochondrial failure impacts brain cells, opening new possibilities for treating severe conditions like epilepsy. These brain organoids mimic real disease processes, allowing scientists to observe mitochondrial dysfunction and test potential treatments.

Brain Cancer Featured Neurology Neuroscience

·December 9, 2024·6 min read

Lab-Grown Tumor Models Mirror Glioblastoma Treatment Response

Glioblastoma organoids, lab-grown replicas of a patient’s tumor, accurately predict how the tumor responds to CAR T cell therapy. This breakthrough allows real-time testing of therapies, showing that responses in the organoid closely mirror those in the patient.

Autism Featured Neuroscience

·October 24, 2024·6 min read

Stem Cell Mini-Brains Unlock Insights into Autism

Researchers have created "mini-brains" using stem cells from patients with a rare form of autism, allowing them to study brain development in detail. These organoids revealed how a genetic mutation in MEF2C disrupts the balance between excitatory and inhibitory neurons, leading to autism.

Featured Neurology Neuroscience

·October 15, 2024·4 min read

Mini Brains Uncover Treatment Leads for Lewy Body Dementia

Lewy body dementia (LBD) is a challenging-to-diagnose neurodegenerative disease with symptoms similar to both Parkinson’s and Alzheimer’s diseases, including hallucinations, cognitive issues, and movement disorders. To study LBD’s progression, researchers developed mini brain models from LBD patient stem cells, replicating key disease characteristics seen in human brains. These models helped identify four promising drugs that may inhibit alpha-synuclein buildup, a key protein associated with LBD.

Featured Neuroethics Neuroscience

·June 20, 2024·4 min read

Organoids and Embryo Models: Redefining Human Individuality?

Advances in organoids and embryonic models raise questions about human individuality. A new study argues these models can reinforce, not weaken, the concept of human individuality when viewed through personhood and sentience frameworks. Researchers emphasize that current technologies are far from achieving personhood in embryo models or organoids. The ethical focus should remain on the wellbeing of actual persons and sentient beings.

Featured Genetics Neurology Neuroscience

·May 14, 2024·6 min read

Mini-Brains from Stem Cells Provide Hope for Alzheimer’s Diagnosis

Researchers developed tiny "mini-brains" from stem cells to help diagnose and treat Alzheimer’s disease. These mini-brains, created from human blood, accurately reflect the pathology of Alzheimer’s on a smaller scale. This innovative technology could revolutionize healthcare, especially for remote communities, by providing a simpler way to diagnose neurological conditions.