Researchers report six minutes of high-intensity exercise on a regular basis can slow brain aging and delay the onset of neurodegenerative diseases such as Alzheimer's and Parkinson's disease. High-intensity exercise increases the production of BDNF, a protein implicated in memory, learning, and brain plasticity, which could protect the brain from age-related cognitive decline.
Mouse study reveals exercise increases dopamine signaling in motor areas of the brain. The findings may explain why exercise eases symptoms of Parkinson's disease.
Spinal cord neurons process pain differently in men and women, a new study reveals.
Researchers report it's easier to control cognitive activity via transcranial magnetic stimulation in people with the Val/Val genetic variant of BDNF.
In the absence of neural activity, BDNF expression can still be activated. The findings shed light on how therapeutic ketamine used has an antidepressant effect and how it works in both the long and short term.
Researchers have identified three biomarkers in blood samples that confirm the link between exercise and improved cognitive function in older adults.
A new 3-D printed biomaterial is able to mimic the properties of living brain tissue. The new material could be used to enhance regenerative medicine therapies.
Researchers launch the first-in-human phase 1 clinical trial to assess the safety and efficacy of a gene therapy which will deliver BDNF to the brains of those with Alzheimer's and mild cognitive impairment.
SSRI's, ketamine, and tricyclic antidepressants all bind with TrkB. The findings challenge the roles serotonin and glutamate receptors play in the effects of antidepressant medications.
Normally bushy networks of neural fibers within fat tissue shrink in the absence of leptin, but grow back when the hormone is administered in drug form. The alterations influence the ability to burn energy stored in fat in mouse models.
Using patient-derived adult stem cells, researchers found fish oil created an antidepressant response.
A global knockout of the thrombin receptor PAR1 accelerates myelin development. The findings could help with the development of treatments for diseases associated with demyelination, like multiple sclerosis.