A new 3-D printed biomaterial is able to mimic the properties of living brain tissue. The new material could be used to enhance regenerative medicine therapies.
A global knockout of the thrombin receptor PAR1 accelerates myelin development. The findings could help with the development of treatments for diseases associated with demyelination, like multiple sclerosis.
Researchers report both negative and positive experiences influence how genetic factors influence the brain and behavior.
Researchers have identified biomarkers that can help predict which patients with Parkinson's disease will suffer from significant cognitive deficits within three years of diagnosis.
In the absence of neural activity, BDNF expression can still be activated. The findings shed light on how therapeutic ketamine used has an antidepressant effect and how it works in both the long and short term.
Scientists have discovered a biological marker that may help to identify which depressed patients will respond to an experimental, rapid-acting antidepressant like ketamine. The brain signal, detectable by noninvasive imaging, also holds clues to the agent's underlying mechanism, which are vital for drug development, say NIH researchers.
Researchers report the gamma-CaMPII protein plays a critical role in learning and memory. The shuttle protein may be dysfunctional in those with Schizophrenia and autism, hindering learning abilities, researchers report.