Obesity is, in part, determined by epigenetic development in the arcuate nucleus of the hypothalamus. Findings suggest developmental epigenetics plays a significant role in both environmental and genetic influences on obesity risk.
Researchers have developed a new sensor that allows scientists to image the brain without missing signals for an extended period of time and deeper in the brain than current technology allows.
Researchers report they have identified the first natural light-gated potassium channel-rhodopsins.
Researchers have identified a molecule in the blood that is produced during exercise. The molecule, Lac-Phe, can effectively reduce food intake and obesity in mouse models.
Hyperactivity in a serotonin-dopamine circuit in the brain appears to be responsible for persistent anorexia in animal models. The DRD1 receptor appears to drive the hyperactivity. Deleting the DRD1 gene restored normal eating behaviors in animals.
Type 1 interferon is a major diver of cognitive impairment and memory loss in mouse models of Alzheimer's disease. Blocking IFN reversed both cognitive impairments and memory deficits in the animal models.
Oleic acid produced in the brain is an essential regulator of processes that enable memory, learning, and mood regulation. Oleic acid, which is abundant in olive oil, also promoted neurogenesis and increases cell proliferation.
Mouse study reveals brain activity patterns associated with memory recall become active when learning by observation.