Several variants of the PIK3CA gene drive brain tumor progression. Two of the variants alter the expression of genes involved in synapses. Read More
Study finds no link between the abundance of herpes viral DNA or RNA and an increased risk of developing Alzheimer's disease. Read More
Genetically silencing mTORC2 in mouse models prolonged lifespan, suppressed seizures, increased long-term memory, and reduced autism-like behaviors. Read More
A new study identifies a novel neural network regulating feeding and mood in response to chronic stress. Inhibiting the POMC to ventral tegmental area circuit increases body weight and food intake while reducing depressive symptoms in mouse models. Read More
Islets of Langerhans in overnourished infant mice showed epigenetic profiles resembling those of much older mice. Read More
Study reveals how CD2AP may enhance Alzheimer's susceptibility. The gene affects neural communication by regulating the levels of regulatory proteins present around synapses. Read More
Seizures associated with Alzheimer's disease in both animal models and humans alter hippocampal neurogenesis. Treating mice with antiseizure medications normalized neurogenesis and improved spatial discrimination. Read More
Being able to put a name to an object involves changing network interactions between different brain regions. Read More
Microbes found in the placenta may play a key role in shaping the developing fetal immune system. Read More
A set of neurons in the basal forebrain may drive aversions to certain foods. Read More
A new study reveals how NCOR1/2 regulates memory involving a newly identified circuit between the lateral hypothalamus and hippocampus. Researchers believe the findings could have implications for future studies related to ASD and neurodegenerative diseases. Read More
Researchers report a common yeast infection can cross the blood-brain barrier, triggering an inflammatory response that results in the formation of granuloma type structures and temporary memory impairments in mice. Read More
