Brain tumors remodel neuronal synapses to promote growth
Several variants of the PIK3CA gene drive brain tumor progression. Two of the variants alter the expression of genes involved in synapses. ... Read More...
Baylor College of Medicine
Is herpes virus infections linked to Alzheimer’s disease?
Study finds no link between the abundance of herpes viral DNA or RNA and an increased risk of developing Alzheimer's disease.... Read More...
New therapeutic strategy may help reverse autism behavioral abnormalities
Genetically silencing mTORC2 in mouse models prolonged lifespan, suppressed seizures, increased long-term memory, and reduced autism-like behaviors.... Read More...
Brain circuit connects feeding and mood in response to stress
A new study identifies a novel neural network regulating feeding and mood in response to chronic stress. Inhibiting the POMC to ventral tegmental area circuit increases body weight and food intake while reducing depressive symptoms in mouse models.... Read More...
From cradle to grave: Postnatal overnutrition linked to aging
Islets of Langerhans in overnourished infant mice showed epigenetic profiles resembling those of much older mice.... Read More...
Gene linked to Alzheimer’s disease is involved in neuronal communication
Study reveals how CD2AP may enhance Alzheimer's susceptibility. The gene affects neural communication by regulating the levels of regulatory proteins present around synapses.... Read More...
Alzheimer’s mouse model seizures disrupt adult neurogenesis
Seizures associated with Alzheimer's disease in both animal models and humans alter hippocampal neurogenesis. Treating mice with antiseizure medications normalized neurogenesis and improved spatial discrimination.... Read More...
Understanding brain activity when you name what you see
Being able to put a name to an object involves changing network interactions between different brain regions.... Read More...
New evidence supports the presence of microbes in the placenta
Microbes found in the placenta may play a key role in shaping the developing fetal immune system.... Read More...
Afraid of food? The answer may be in the basal forebrain
A set of neurons in the basal forebrain may drive aversions to certain foods. ... Read More...
Unexpected Link Between Feeding and Memory Brain Areas Discovered
A new study reveals how NCOR1/2 regulates memory involving a newly identified circuit between the lateral hypothalamus and hippocampus. Researchers believe the findings could have implications for future studies related to ASD and neurodegenerative diseases.... Read More...
Fungi Causes Brain Infection and Memory Impairments: Mouse Study
Researchers report a common yeast infection can cross the blood-brain barrier, triggering an inflammatory response that results in the formation of granuloma type structures and temporary memory impairments in mice. ... Read More...