Type 1 interferon is a major diver of cognitive impairment and memory loss in mouse models of Alzheimer's disease. Blocking IFN reversed both cognitive impairments and memory deficits in the animal models.
Oleic acid produced in the brain is an essential regulator of processes that enable memory, learning, and mood regulation. Oleic acid, which is abundant in olive oil, also promoted neurogenesis and increases cell proliferation.
Combining deep-brain stimulation with intracranial EEG, researchers achieved an individualized understanding of specific brain networks that contributed to an individual's depression symptoms and identified stimulation patterns best suited to each patient for symptom relief.
Blood tests revealed specific epigenetic biomarkers for schizophrenia. Researchers applied machine learning to analyze the CoRSIVs region of the human genome to identify the schizophrenia biomarkers. Testing the model with an independent data set revealed the AI technology can detect schizophrenia with 80% accuracy.
The brain regulates both eating for hunger and pleasure through serotonin-producing neurons in the midbrain, but the different types of feeding are wired by independent circuits that do not influence the other type of feeding.