Iron levels in the basal ganglia steadily increase throughout development and, in two sub-regions, continue to increase into adulthood. Decreased levels of iron in the putamen was correlated with impaired cognitive performance involving reasoning and spatial processing. Findings suggest the brain requires iron for healthy cognitive development.
Different types of reward have unique effects on the basal ganglia nuclei. Food rewards influence the left hemisphere of the brain, while erotic rewards engage the right lateral globus and left caudate. Financial rewards engage the basal ganglia bilaterally.
Researchers have identified a comprehensive circuit mechanism that governs how emotional states can influence movement through connections in the basal ganglia. The mechanism represents a way in which emotional states relate to changes in action control in depression, anxiety, and OCD.
The medial prefrontal cortex persistently encodes value based decision variables.
A pathway linking the basal ganglia to the thalamus enhances sensory discrimination and is used to suppress 'background noise'. The pathway, which is controlled by the prefrontal cortex, selectively suppresses sensory input as it flows to the thalamus.
Researchers have pinpointed how brain activity changes in mouse models of Parkinson's disease, providing clues as to what may drive symptoms of the disease in humans.
Researchers report there are two distinct ways in which we make temporal predictions, and these rely on different parts of the brain. The findings offer a new perspective on how humans calculate when to make a move.
Researchers report they have discovered the region of the brain that registers excitement over a preferred food option. The study reports the findings could help develop new therapies and treatments to potentially combat obesity and encourage healthier eating.
A new study reports those with ADHD are at an increased risk of developing Parkinson's disease. The study reveals people with ADHD are twice as likely to develop early onset Parkinson's between the ages of 21-66. Additionally, those who are prescribed stimulant medications to help reduce ADHD symptoms, including Ritalin and Adderal, are at a 6-8 times increased risk of developing Parkinson's.
Researchers say those who use both cannabis and nicotine have greater brain connectivity that those who take one or the other. The networks of those who used both substances closely resembled those who people who took neither drug.