A healthy and diverse microbiome is essential for quickly clearing viral infections in the nervous system to prevent risks associated with multiple sclerosis. Mice with lower gut bacteria had weaker immune responses and were unable to eliminate viruses, leading to worsening paralysis. Those treated with antibiotics before infection had fewer microglia.
Understanding the complexity of the human microbiome may help unlock mysteries behind health and psychological illnesses.
10(Z)-hexadecenoic acid, a fatty acid found in the soil based bacterium Mycobacterium vaccae, interacts with immune cells to inhibit pathways that drive inflammation and increases resilience to stress. Researchers say the findings could bring us one step closer to developing a microbe-based "stress vaccine".
Our circadian rhythm may explain why we are more prone to different health conditions at different points throughout the day.
Researchers have implicated Porphyromonas gingivalis, a bacteria commonly associated with gum disease, in Alzheimer's pathology. The study reports oral Pg infections leads to a colonization and increased production of amyloid beta.
Researchers re-purposed CRISPR gene editing technology to study genes targeted by particular antibiotics. The study sheds light on how pharmacologists can improve existing antibiotics and develop new ones.
Researchers have identified two new species of bacteria in the blood of patients in China. The bacterias are in the Enterobacter genus and are resistant to multiple antibiotics. Enterobacter has previously been linked to meningitis and other serious medical conditions.
Researchers have developed a new mathematical model that analyzes the interactions between gut bacteria.
A new mouse study reveals long term exposure to bacteria associated with periodontal disease causes neuroinflammation and neurodegeneration, leading to similar effects of Alzheimer's disease. Researchers report periodontal disease may be an initiator of Alzheimer's.
Researchers report the personal odors of healthy animals change when they share an environment with a sick animal. The findings suggest these changes could impact social contact and patterns of disease spread.
Researchers report differences in oral microbial gene expression may distinguish children with ASD from their peers not on the spectrum. The study suggests GI microbiome disruptions, previously identified in children with ASD, may extend to the mouth and throat.
A new mouse study reveals pups of mothers who faced prenatal stress and who were exposed, by birth, to maternal vaginal microbiota had decreased body weight and exhibited increased stress hormones as adults.