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autoimmune diseases

·April 29, 2025·3 min read

New Biomarker Predicts MS Progression

Researchers have identified a new biomarker in multiple sclerosis (MS): the thickness of the inflammatory rim surrounding brain lesions predicts how quickly and severely the disease progresses. By combining PET imaging and post-mortem brain analysis, the study showed that thicker rims lead to more aggressive brain damage.

Featured Genetics Neurology Neuroscience

·January 7, 2025·8 min read

AI Predicts Autoimmune Disease Progression with New Genetic Tool

Researchers have developed a Genetic Progression Score (GPS) using artificial intelligence to predict the progression of autoimmune diseases from preclinical symptoms to full disease. The GPS model integrates genetic data and electronic health records to provide personalized risk scores, improving prediction accuracy by 25% to 1,000% over existing models.

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Featured Neurology Neuroscience

·October 21, 2024·4 min read

Vitamin D Deficiency in Childhood Linked to Higher Autoimmune Risk

A recent study found that vitamin D deficiency during childhood accelerates the aging of the thymus, a crucial organ in training immune cells. As the thymus ages, it becomes less effective at filtering out cells that could mistakenly attack the body's own tissues, increasing the risk of autoimmune diseases like type 1 diabetes.

Featured Neurology Neuroscience

·October 17, 2024·4 min read

“Brain on Fire”: When Antibodies Attack the Brain

Anti-NMDAR encephalitis, a rare autoimmune disease, can cause extreme psychiatric symptoms such as hallucinations, paranoia, and memory loss, often mimicking bipolar disorder or schizophrenia. This condition, often affecting women in their 20s to 30s, results from antibodies attacking brain receptors essential for cognition and memory.

Featured Genetics Neurology Neuroscience

·August 28, 2024·4 min read

Increase in Protein Linked to Salt Intake Implicated in Multiple Sclerosis

Researchers have uncovered that increased levels of the protein PRDM1-S, triggered by high salt intake, disrupt immune regulation and contribute to autoimmune diseases like multiple sclerosis (MS). This discovery reveals how environmental factors, such as diet, can influence genetic mechanisms, leading to T cell dysfunction. The findings suggest that targeting PRDM1-S could lead to new treatments for a range of autoimmune disorders.

Featured Neurology Neuroscience

·June 7, 2024·5 min read

Epstein-Barr Virus Plays Critical Role in Multiple Sclerosis

Epstein-Barr Virus (EBV) may cause multiple sclerosis (MS) through higher levels of immune cross-reactivity than previously thought. Researchers found that T-cells targeting EBV can also recognize brain proteins, a misdirection seen in both MS patients and healthy individuals.

Featured Neurology Neuroscience

·May 26, 2024·7 min read

Nightmares May Signal Autoimmune Flares

A new study suggests that increased nightmares and hallucinations can signal the onset of autoimmune diseases like lupus. The research highlights the need for greater recognition of these symptoms as early indicators of disease flares.

Featured Neurology Neuroscience

·May 2, 2024·6 min read

The Brain’s Role in Immune Control

Researchers discovered that the brain can significantly influence the immune system, particularly its inflammatory responses. The study utilized mice to show that the brain can detect and adjust levels of inflammation via a specific brain circuit involving the caudal nucleus of the solitary tract.

Featured Neurology Neuroscience

·May 2, 2024·7 min read

Myelin Repair Provides Novel Multiple Sclerosis Treatment

Researchers discovered a promising treatment for multiple sclerosis (MS) using a novel protein function inhibitor, ESI1, which effectively regenerates myelin—a crucial protective coating on nerve cells that deteriorates in MS. The study showcases that ESI1 reactivates the brain's capacity to produce myelin, overcoming traditional barriers that have hindered myelin regeneration.

Featured Neurology Neuroscience

·April 19, 2024·7 min read

Blood Test Predicts Multiple Sclerosis Years Before Symptoms Appear

Researchers identified a specific pattern of autoantibodies in the blood that precedes the clinical onset of multiple sclerosis (MS), potentially paving the way for early diagnosis and treatment. Their study found that 10% of MS patients displayed a unique set of autoantibodies against both human proteins and common pathogens like the Epstein-Barr Virus years before showing symptoms.

Featured Neurology Neuroscience

·June 12, 2023·8 min read

Cellular Custodians: ‘Big Eater’ Macrophages May Hold Key to Autoimmune Disease Treatment

The mysterious workings of tingible body macrophages (TBMs) have been substantially demystified. These TBMs, a subtype of macrophages within our lymph nodes, were found to devour antibody-producing B cells, a function essential in defending our bodies against harmful pathogens.

Featured Neurology Neuroscience

·February 15, 2023·4 min read

Multiple Sclerosis Discovery Could End Disease’s Chronic Inflammation

Blocking the activity of the reactor called the aryl hydrocarbon receptor in T cells resulted in both a decrease in inflammation and recovery in mouse models of multiple sclerosis.

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autoimmune diseases

New Biomarker Predicts MS Progression

AI Predicts Autoimmune Disease Progression with New Genetic Tool

Vitamin D Deficiency in Childhood Linked to Higher Autoimmune Risk

“Brain on Fire”: When Antibodies Attack the Brain

Increase in Protein Linked to Salt Intake Implicated in Multiple Sclerosis

Epstein-Barr Virus Plays Critical Role in Multiple Sclerosis

Nightmares May Signal Autoimmune Flares

The Brain’s Role in Immune Control

Myelin Repair Provides Novel Multiple Sclerosis Treatment

Blood Test Predicts Multiple Sclerosis Years Before Symptoms Appear

Cellular Custodians: ‘Big Eater’ Macrophages May Hold Key to Autoimmune Disease Treatment

Multiple Sclerosis Discovery Could End Disease’s Chronic Inflammation

Gene Therapy Restores Hearing in Those with Deafness

Forever Chemicals May Disrupt Brain Development

Kids Outsmart AI in Puzzle Game That Builds Critical Thinking

Drug-Coated Neural Implants Reduce Immune Rejection

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