The number of relapses in patients with relapsing-remitting multiple sclerosis was better controlled and symptoms of disability were stabilized or improved when patients who discontinued fingolimod changed to either ocrelizumab or natalizumab.
Diets high in guar gum, a dietary fiber and common food additive extracted from guar beans, limit inflammation and delay the onset of multiple sclerosis in mouse models.
Researchers propose a new model for Alzheimer's disease (AD2) that considers the neurodegenerative disease as an autoimmune disease that attacks the brain. Considering Alzheimer's as an autoimmune disorder could spark a new line of therapies to treat the disease.
Children who contracted COVID-19 are at increased risk of being diagnosed with Type 1 diabetes. Researchers found a 72% increase in new Type 1 diabetes cases in those under 18 who contracted COVID-19.
Researchers reveal significant differences in gut bacteria in patients with multiple sclerosis compared to those without the autoimmune disease. The study also uncovered novel mechanisms by which the bacteria may influence the disease.
Study reveals a direct link between vitamin D deficiency and chronic inflammation. Researchers suggest boosting vitamin D in those with a deficiency may help to reduce inflammation.
New abortion bans and restrictions could result in life-threatening consequences for women of childbearing age with epilepsy, multiple sclerosis, and migraine due to restrictions placed on their ability to access life-saving medications. Patients in states with strict abortion restrictions are reporting they are unable to access teratogenic drugs to treat their conditions, including methotrexate, as the medications can induce abortion.
Study reveals an association between signal detection theory, brain activation patterns, and subjective state fatigue. In those with multiple sclerosis, greater effects of fatigue were seen.
In the first year after a diagnosis of multiple sclerosis, 60% of patients experience fatigue, 50% experience pain, 47% have symptoms of depression, and 39% report increased anxiety. Researchers say urgent, non-pharmaceutical therapies should be provided for newly diagnosed MS patients to help reduce both pain and mental health symptoms.
In rheumatoid arthritis, inflammation in one joint is transmitted to other joints via the sensory neuron connections in the spinal cord, leading to inflammation in the other joints. Inflammation in one joint led to an increase in ATP in other joints, which triggered an increase of a signaling molecule that resulted in inflammation. Blocking the pathway reduced the spread of inflammation.