Some of the T cell epitopes targeting myelin in monkeys were the same as those found in humans. Researchers say linking these specific cells opens the doors to developing antiviral therapies that could be useful to treat newly diagnosed cases of MS in humans. Read More
Study finds signs of IgA antibodies in the cerebrospinal fluid of patients with multiple sclerosis during a flare-up of the disease, but not when the patients are in remission. The findings suggest gut immune cells are involved in relapse episodes of multiple sclerosis. Read More
Poor sleep and inadequate oxygen supply associated with obstructive sleep apnea appears to affect cytokines. This could explain the link between OSA and an increased risk of autoimmune disorders, such as rheumatoid arthritis. Read More
TEPP-46, a drug developed for the treatment of cancer and showed promise for the treatment of multiple sclerosis, could make MS symptoms worse, a new study reports. The drug appears to redirect inflammation away from the spinal cord and directly into the brain. Read More
A new intranasal delivery system shows promise in reducing neuroinflammation and slowing the progression of multiple sclerosis. Read More
By fusing a cytokine to a blood protein, researchers have developed a new therapy to help treat multiple sclerosis. Read More
Gamma interferons, a type of immune cell that induces and modulates several immune system responses, may also play a role in preventing depression. Read More
Women who have been pregnant were diagnosed with their first multiple sclerosis symptoms, on average, 3.3 years later than women with MS who had never become pregnant. Read More
Specific combinations of microorganisms in the gut can worsen symptoms of multiple sclerosis in mouse models of the autoimmune disease. Read More
Decreasing the amount of Reelin significantly protected against disease symptoms and promoted recovery in symptomatic animal models of multiple sclerosis. Reelin levels appear to correlate with MS severity and stages. Researchers report lowering levels of the protein could be a potential avenue of treatment for the autoimmune disorder. Read More
Human iPSCs transplanted into animal models of multiple sclerosis help repair cell damage and restore function. Read More
A new study reveals why women are more likely to develop autoimmune conditions like lupus and Sjögren's syndrome, and men are more likely to develop schizophrenia. Researchers implicated the C4 gene in sex-based risk factors for autoimmune and psychiatric disorders. Read More