Blood clotting proteins in urine discovered as biomarkers of lupus nephritis
Clotting proteins are elevated in the urine of patients with lupus nephritis. The findings provide a new biomarker for the autoimmune disease.... Read More...
autoimmune diseases
Vaccinations not a risk factor for multiple sclerosis
A study of over 200,000 people found no evidence that vaccinations increase the risk of developing multiple sclerosis, or the onset of an initial MS episode. ... Read More...
Differences in MS patients’ cerebrospinal fluid may be key to drugs that halt progression
Ceramide exposure impairs the ability for neurons to make energy by directly damaging mitochondria. Additionally, ceramides force neurons to rapidly uptake glucose in order to provide cellular energy. ... Read More...
Are the ‘viral’ agents of MS, ALS and schizophrenia buried in our genome?
Retroviruses may be a missing causal link in diseases like ALS, multiple sclerosis and schizophrenia.... Read More...
Brain on Fire: Puzzling brain disease could now be better diagnosed and treated
A rare autoimmune disorder popularized by the autobiography and movie "Brain on Fire" is triggered by an attack on NMDA receptors. The disease occurs when antibodies attack NMDA receptors in the brain, leading to memory loss, intellectual changes, seizures, and death. ... Read More...
B cells off the rails early in lupus
A key finding in the origins of lupus has been discovered. In those with systemic lupus erythematosus, B cells are abnormally activated. This results in the production of antibodies which react against the patient's own tissue, causing a range of symptoms including rashes, joint pain, and fatigue. ... Read More...
Newly discovered immune cells at the frontline of HIV infection
A newly discovered subset of dendritic cells have been implicated in sexually transmitted HIV infection. The CD11c+ dendritic cells are found in human genital tissue at the epithelial level. They are the first immune cells to interact with the HIV virus. The cells directly transfer the virus to CD4 T cells, making them key drivers in HIV transmission.... Read More...
Fibromyalgia linked to variations in microbiome composition
Using a range of clinical techniques, including deep learning, researcher identify changes in the microbiome of people with fibromyalgia which were not associated with diet, medications or aging. Additionally, the severity of symptoms was directly correlated with an increased presence, or more pronounced absence, of certain bacterias.... Read More...
Women caught in a pickle by their own immune systems
Pregnancy Compensation Hypothesis may explain why women are more prone to developing autoimmune diseases, like multiple sclerosis and lupus, than men.... Read More...
12 genes at the root of multiple sclerosis identified
12 genes associated with familial multiple sclerosis have been identified. The findings provide a molecular rationale for the chronic inflammation, demyelination and neurodegeneration associated with MS. Identifying new genetic targets could help with the development of novel treatments to prevent multiple sclerosis in those with a genetic risk.... Read More...
Nanotechnology treatment reverses multiple sclerosis in mice
Extracting nanosized exosomes from bone marrow stem cells and injecting them into mice, researchers reverse symptoms of multiple sclerosis.... Read More...
New compounds could be used to treat autoimmune disorders
Researchers have developed small molecules that inhibit one of the main enzymes implicated in autoimmune response. The research could lead to potential new medications for a range of autoimmune diseases.... Read More...